{"entity":{"id":"marco-vignetti","kind":"person","name":"Marco Vignetti","aka":[],"tldr":"Haematologist who presides over GIMEMA, Italy's adult haematological malignancies cooperative group, and co-authored its chemotherapy-free Ph+ ALL trial.","summary":"Marco Vignetti is President of Fondazione GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto), the Italian cooperative group that runs multicentre trials in adult haematological malignancies. He has co-authored landmark GIMEMA studies including the dasatinib-blinatumomab trial in Philadelphia-positive acute lymphoblastic leukaemia and the description of NPM1 mutations in normal-karyotype AML.","asOf":"2026-09-10","links":[{"label":"Society page","url":"https://www.gimema.it/organigramma/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Vignetti+M%5BAuthor%5D"}],"tags":["leadership","clinician-scientist","leukaemia","clinical trials"],"related":[],"cancers":["all-leukemia","aml"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["gimema"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"President","institutionId":"gimema","specialisms":["Haematology","Acute leukaemia","Clinical trials"],"profiles":[{"label":"Society page","url":"https://www.gimema.it/organigramma/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Vignetti+M%5BAuthor%5D"}],"papers":[{"title":"Dasatinib-Blinatumomab for Ph-Positive Acute Lymphoblastic Leukemia in Adults","journal":"New England Journal of Medicine","year":2020,"url":"https://doi.org/10.1056/NEJMoa2016272","doi":"10.1056/NEJMoa2016272"},{"title":"Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype","journal":"New England Journal of Medicine","year":2005,"url":"https://doi.org/10.1056/NEJMoa041974","doi":"10.1056/NEJMoa041974"}]},"route":"/people/marco-vignetti/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"}],"company":[{"id":"gimema","kind":"company","name":"GIMEMA","route":"/companies/gimema/"}]}}