{"entity":{"id":"keith-stewart","kind":"person","name":"A. Keith Stewart","aka":[],"tldr":"Keith Stewart is a myeloma researcher who leads Canada's largest cancer centre.","summary":"A. Keith Stewart is Director of the Princess Margaret Cancer Centre and Vice President, Cancer, at University Health Network, having previously worked at the Mayo Clinic Comprehensive Cancer Center in Arizona. He is a multiple myeloma researcher known for leading the ASPIRE trial of carfilzomib in relapsed disease and for myeloma genomics studies. His selected paper reports the combination of carfilzomib, lenalidomide and dexamethasone for relapsed multiple myeloma. He now combines academic leadership of Canada's largest cancer centre with continued work in myeloma and cancer genomics.","asOf":"2026-09-08","links":[{"label":"Princess Margaret","url":"https://www.uhn.ca/PrincessMargaret"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Stewart%20AK%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["multiple-myeloma"],"sections":[],"technologies":[],"targets":[],"drugs":["carfilzomib","lenalidomide"],"companies":[],"institutions":["princess-margaret","mayo-clinic-arizona"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Director, Princess Margaret Cancer Centre; Vice President, Cancer, University Health Network","institutionId":"princess-margaret","specialisms":["Multiple myeloma","Cancer genomics","Academic leadership"],"profiles":[{"label":"Princess Margaret","url":"https://www.uhn.ca/PrincessMargaret"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Stewart%20AK%5BAuthor%5D"}],"papers":[{"title":"Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma","journal":"New England Journal of Medicine","year":2015,"url":"https://doi.org/10.1056/NEJMoa1411321","doi":"10.1056/NEJMoa1411321"}]},"route":"/people/keith-stewart/","neighbours":{"cancer":[{"id":"multiple-myeloma","kind":"cancer","name":"Multiple myeloma","route":"/cancers/multiple-myeloma/"}],"drug":[{"id":"carfilzomib","kind":"drug","name":"Carfilzomib","route":"/drugs/carfilzomib/"},{"id":"lenalidomide","kind":"drug","name":"Lenalidomide","route":"/drugs/lenalidomide/"}],"institution":[{"id":"mayo-clinic-arizona","kind":"institution","name":"Mayo Clinic Comprehensive Cancer Center in Arizona","route":"/institutions/mayo-clinic-arizona/"},{"id":"princess-margaret","kind":"institution","name":"Princess Margaret Cancer Centre","route":"/institutions/princess-margaret/"}]}}