{"entity":{"id":"karolinska","kind":"institution","name":"Karolinska University Hospital","aka":["Karolinska Comprehensive Cancer Center"],"tldr":"Sweden's leading cancer hospital, linked to the Karolinska Institutet and Nobel Assembly, with strong registry-based research.","summary":"Karolinska University Hospital in Stockholm is Sweden's leading cancer hospital, linked to the Karolinska Institutet and the Nobel Assembly, and ranks thirty-ninth in the Newsweek/Statista oncology list. Its Comprehensive Cancer Centre is known for registry-based research, because Sweden's national quality registries make real-world evidence and registry-randomised trials possible, and it collaborates with the Skandion proton clinic in Uppsala; Per Hall, Jonas Bergh and Thomas Helleday are among the people OnCo lists. OnCo links it to the ALASCCA aspirin trial, to the Swedish registry study of HPV vaccination and cervical cancer, and to ideas on randomising inside cancer registries and a registry-based MCED trial. Whether registry designs can carry regulatory weight outside the Nordics is the open question. Its registry and haematology programmes are listed below.","asOf":"2026-09-04","wikipedia":"https://en.wikipedia.org/wiki/Karolinska_University_Hospital","links":[{"label":"Official website","url":"https://www.karolinska.se"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":["gamma-knife","radiosurgery-srs"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["real-world-evidence"],"trials":[],"people":["per-hall","rolf-kiessling","hans-gustaf-ljunggren","thomas-helleday","jonas-bergh","patrik-rossi"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Stockholm","country":"SE","lat":59.35,"lng":18.034,"institutionType":"university","website":"https://www.karolinska.se","newsweekOncology2026":39,"university":"Karolinska Institutet","programs":["Registry research","Haematology"]},"route":"/institutions/karolinska/","neighbours":{"technology":[{"id":"gamma-knife","kind":"technology","name":"Gamma Knife","route":"/technologies/gamma-knife/"},{"id":"radiosurgery-srs","kind":"technology","name":"Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS)","route":"/technologies/radiosurgery-srs/"}],"term":[{"id":"real-world-evidence","kind":"term","name":"Real-world evidence","route":"/terms/real-world-evidence/"}],"person":[{"id":"hans-gustaf-ljunggren","kind":"person","name":"Hans-Gustaf Ljunggren","route":"/people/hans-gustaf-ljunggren/"},{"id":"jonas-bergh","kind":"person","name":"Jonas Bergh","route":"/people/jonas-bergh/"},{"id":"patrik-rossi","kind":"person","name":"Patrik Rossi","route":"/people/patrik-rossi/"},{"id":"per-hall","kind":"person","name":"Per Hall","route":"/people/per-hall/"},{"id":"rolf-kiessling","kind":"person","name":"Rolf Kiessling","route":"/people/rolf-kiessling/"},{"id":"thomas-helleday","kind":"person","name":"Thomas Helleday","route":"/people/thomas-helleday/"}],"paper":[{"id":"paper-screentrustcad-dembrower-lancet-digit-health-2023","kind":"paper","name":"Artificial intelligence for breast cancer detection in screening mammography in Sweden: a prospective, population-based, paired-reader, non-inferiority study (ScreenTrustCAD)","route":"/key-papers/paper-screentrustcad-dembrower-lancet-digit-health-2023/"},{"id":"paper-swedish-rectal-cancer-trial-preoperative-radiotherapy-nejm-1997","kind":"paper","name":"Improved survival with preoperative radiotherapy in resectable rectal cancer (Swedish Rectal Cancer Trial)","route":"/key-papers/paper-swedish-rectal-cancer-trial-preoperative-radiotherapy-nejm-1997/"},{"id":"paper-hpv-vaccine-sweden-nejm-2020","kind":"paper","name":"Swedish registry study: HPV vaccination almost eliminates cervical cancer when given before 17","route":"/key-papers/paper-hpv-vaccine-sweden-nejm-2020/"}],"trial":[{"id":"alascca","kind":"trial","name":"ALASCCA","route":"/trials/alascca/"},{"id":"norpact-1","kind":"trial","name":"NORPACT-1","route":"/trials/norpact-1/"},{"id":"screentrustcad","kind":"trial","name":"ScreenTrustCAD","route":"/trials/screentrustcad/"},{"id":"senomac","kind":"trial","name":"SENOMAC","route":"/trials/senomac/"},{"id":"stockholm-iii","kind":"trial","name":"Stockholm III","route":"/trials/stockholm-iii/"}],"idea":[{"id":"idea-moon-adult-late-effects-registry","kind":"idea","name":"A lifelong late-effects registry linked to every treatment for adult survivors","route":"/ideas/idea-moon-adult-late-effects-registry/"},{"id":"idea-reg-aspirin-pik3ca-implementation","kind":"idea","name":"Get biomarker-directed aspirin after colorectal surgery into labels and guidelines","route":"/ideas/idea-reg-aspirin-pik3ca-implementation/"},{"id":"idea-nl-bariatric-cancer-registry-linkage","kind":"idea","name":"Link bariatric and GLP-1 registries to cancer registries in every country that has both","route":"/ideas/idea-nl-bariatric-cancer-registry-linkage/"},{"id":"idea-tr1-registry-embedded-randomisation","kind":"idea","name":"Randomise inside the cancer registry: registry-based trials for everyday questions","route":"/ideas/idea-tr1-registry-embedded-randomisation/"},{"id":"idea-prev-mced-registry-randomised","kind":"idea","name":"Registry-based randomised MCED trial: a million people, no study visits","route":"/ideas/idea-prev-mced-registry-randomised/"},{"id":"idea-data-registry-based-rcts","kind":"idea","name":"Registry-based randomised trials for oncology comparative effectiveness","route":"/ideas/idea-data-registry-based-rcts/"}],"institution":[{"id":"capio-st-goran","kind":"institution","name":"Capio S:t Göran's Hospital","route":"/institutions/capio-st-goran/"},{"id":"helsinki-hus","kind":"institution","name":"HUS Comprehensive Cancer Center, Helsinki University Hospital","route":"/institutions/helsinki-hus/"},{"id":"linkoping-university-hospital","kind":"institution","name":"Linköping University Hospital Cancer Center","route":"/institutions/linkoping-university-hospital/"},{"id":"orebro-university-hospital","kind":"institution","name":"Örebro University Hospital","route":"/institutions/orebro-university-hospital/"},{"id":"oeci","kind":"institution","name":"Organisation of European Cancer Institutes","route":"/institutions/oeci/"},{"id":"oslo-radium-hospital","kind":"institution","name":"Oslo University Hospital, The Norwegian Radium Hospital","route":"/institutions/oslo-radium-hospital/"},{"id":"sahlgrenska","kind":"institution","name":"Sahlgrenska University Hospital / Sahlgrenska Center for Cancer Research","route":"/institutions/sahlgrenska/"},{"id":"lund-skane","kind":"institution","name":"Skåne University Hospital / Lund University Cancer Centre","route":"/institutions/lund-skane/"},{"id":"sgccn","kind":"institution","name":"Stockholm Gotland Comprehensive Cancer Network (SGCCN)","route":"/institutions/sgccn/"},{"id":"uppsala-akademiska","kind":"institution","name":"Uppsala University Hospital / Uppsala University","route":"/institutions/uppsala-akademiska/"}],"company":[{"id":"nordic-lymphoma-group","kind":"company","name":"Nordic Lymphoma Group","route":"/companies/nordic-lymphoma-group/"}]}}