{"entity":{"id":"juravinski","kind":"institution","name":"Juravinski Cancer Centre / Escarpment Cancer Research Institute","aka":["JCC","Hamilton Health Sciences cancer program"],"tldr":"Hamilton's regional cancer centre with McMaster University, home of the trials that made hypofractionated breast radiotherapy standard and of brain tumour stem cell research.","summary":"The Juravinski Cancer Centre is the tertiary cancer centre of Hamilton Health Sciences and McMaster University, serving south-central Ontario, with the Escarpment Cancer Research Institute as its research arm. The Ontario Clinical Oncology Group at McMaster, founded by Mark Levine, ran pragmatic trials that changed practice, above all Tim Whelan's trial showing three-week hypofractionated whole-breast radiotherapy is as effective as five weeks, and Ralph Meyer led the CCTG HD.6 trial in Hodgkin lymphoma. Sheila Singh's laboratory studies brain tumour-initiating cells in glioblastoma and medulloblastoma, and Jonathan Bramson's T-cell antigen coupler technology offers an alternative to CAR-T. The centre runs one of Ontario's largest transplant and haematology programmes.","asOf":"2026-09-09","links":[{"label":"Juravinski Cancer Centre","url":"https://www.hamiltonhealthsciences.ca/areas-of-care/cancer-care/"},{"label":"Escarpment Cancer Research Institute","url":"https://ecri.mcmaster.ca"}],"tags":[],"related":[],"cancers":["breast-hr-positive","hodgkin-lymphoma","glioblastoma","medulloblastoma"],"sections":["radiation"],"technologies":["imrt-igrt","car-t","allogeneic-hsct"],"targets":[],"drugs":[],"companies":["cctg"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":["chris-hillis","timothy-whelan"],"bottlenecks":["b-trial-design"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Hamilton, ON","country":"CA","lat":43.241,"lng":-79.891,"institutionType":"cancer-center","website":"https://www.hamiltonhealthsciences.ca/areas-of-care/cancer-care/","university":"McMaster University","programs":["Radiotherapy trials (hypofractionation)","Lymphoma trials","Brain tumour stem cells","Engineered T cells (TAC)"]},"route":"/institutions/juravinski/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"},{"id":"hodgkin-lymphoma","kind":"cancer","name":"Hodgkin lymphoma","route":"/cancers/hodgkin-lymphoma/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"medulloblastoma","kind":"cancer","name":"Medulloblastoma","route":"/cancers/medulloblastoma/"}],"section":[{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"}],"technology":[{"id":"allogeneic-hsct","kind":"technology","name":"Allogeneic stem cell transplantation","route":"/technologies/allogeneic-hsct/"},{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"company":[{"id":"cctg","kind":"company","name":"Canadian Cancer Trials Group (CCTG)","route":"/companies/cctg/"}],"person":[{"id":"chris-hillis","kind":"person","name":"Chris Hillis","route":"/people/chris-hillis/"},{"id":"timothy-whelan","kind":"person","name":"Timothy J. Whelan","route":"/people/timothy-whelan/"}],"bottleneck":[{"id":"b-trial-design","kind":"bottleneck","name":"Trial design, endpoints and cost","route":"/bottlenecks/b-trial-design/"}],"institution":[{"id":"ontario-health-cancer-care-ontario","kind":"institution","name":"Ontario Health (Cancer Care Ontario)","route":"/institutions/ontario-health-cancer-care-ontario/"}]}}