{"entity":{"id":"joe-chang","kind":"person","name":"Joe Y. Chang","aka":[],"tldr":"Led the trials comparing stereotactic radiotherapy with surgery for operable early lung cancer.","summary":"Joe Chang led the pooled STARS and ROSEL analysis and the revised STARS trial suggesting stereotactic ablative radiotherapy matches lobectomy for operable stage I NSCLC, results that opened the surgery-versus-SABR debate. He directs thoracic radiation oncology at MD Anderson and studies proton therapy and radiotherapy-immunotherapy combinations.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Chang%20JY%5BAuthor%5D%20stereotactic%20ablative%20lung"}],"tags":["radiotherapy","sbrt","lung"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":["sbrt","proton-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":["md-anderson"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Professor of Radiation Oncology, MD Anderson Cancer Center","institutionId":"md-anderson","specialisms":["Stereotactic ablative radiotherapy","Proton therapy","Lung cancer","Immunotherapy-radiotherapy combinations"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Chang%20JY%5BAuthor%5D%20stereotactic%20ablative%20lung"}],"papers":[{"title":"Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials","journal":"Lancet Oncology","year":2015,"doi":"10.1016/S1470-2045(15)70168-3"},{"title":"Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery","journal":"Lancet Oncology","year":2021,"doi":"10.1016/S1470-2045(21)00401-0"}],"orcid":"0000-0002-8435-2083"},"route":"/people/joe-chang/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"technology":[{"id":"proton-therapy","kind":"technology","name":"Proton therapy","route":"/technologies/proton-therapy/"},{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"institution":[{"id":"md-anderson","kind":"institution","name":"MD Anderson Cancer Center","route":"/institutions/md-anderson/"}]}}