{"entity":{"id":"jean-bourhis","kind":"person","name":"Jean Bourhis","aka":[],"tldr":"Radiation oncologist behind the MACH-NC meta-analyses that proved chemoradiotherapy helps head and neck cancer, and the first FLASH-treated patient.","summary":"Jean Bourhis led the MACH-NC individual patient data meta-analyses showing that concomitant chemotherapy adds about 6.5% absolute survival to radiotherapy in head and neck cancer, and the MARCH meta-analysis of altered fractionation, both of which set global standards. He treated the first patient with FLASH radiotherapy in 2018 and leads the clinical FLASH programme at CHUV.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Bourhis%20J%5BAuthor%5D%20head%20neck%20meta-analysis%20OR%20FLASH"}],"tags":["head-and-neck","radiotherapy","flash"],"related":[],"cancers":["head-and-neck"],"sections":[],"technologies":["imrt-igrt","flash-rt"],"targets":[],"drugs":[],"companies":[],"institutions":["chuv-lausanne"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["radiotherapy-and-oncology"],"dependsOn":[],"notes":[],"role":"Head of Radiation Oncology, Lausanne University Hospital (CHUV)","institutionId":"chuv-lausanne","specialisms":["Head and neck radiotherapy","Meta-analysis","Altered fractionation","FLASH radiotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Bourhis%20J%5BAuthor%5D%20head%20neck%20meta-analysis%20OR%20FLASH"}],"papers":[{"title":"Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients","journal":"Radiotherapy and Oncology","year":2009,"doi":"10.1016/j.radonc.2009.04.014"},{"title":"Treatment of a first patient with FLASH-radiotherapy","journal":"Radiotherapy and Oncology","year":2019,"doi":"10.1016/j.radonc.2019.06.019"}],"orcid":"0000-0001-5162-1171"},"route":"/people/jean-bourhis/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"}],"technology":[{"id":"flash-rt","kind":"technology","name":"FLASH radiotherapy","route":"/technologies/flash-rt/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"institution":[{"id":"chuv-lausanne","kind":"institution","name":"Lausanne University Hospital (CHUV) / Ludwig Institute Lausanne","route":"/institutions/chuv-lausanne/"}],"journal":[{"id":"radiotherapy-and-oncology","kind":"journal","name":"Radiotherapy and Oncology","route":"/journals/radiotherapy-and-oncology/"}],"trial":[{"id":"nivopostop","kind":"trial","name":"NIVOPOSTOP (GORTEC 2018-01)","route":"/trials/nivopostop/"}]}}