{"entity":{"id":"intraop-medical","kind":"company","name":"IntraOp Medical","aka":[],"tldr":"IntraOp makes the Mobetron, a mobile electron-beam machine that can be wheeled into an operating theatre to give a single, targeted dose of radiation to the tumour bed during cancer surgery, and it is also being used in the first human trials of ultra-fast FLASH radiotherapy.","summary":"IntraOp Medical Corporation manufactures the Mobetron, introduced in 1993 as the first mobile electron linear accelerator for intraoperative radiotherapy (IORT). The self-shielded unit delivers electron beams directly to the tumour bed during surgery, sparing surrounding organs. The company reports more than forty units at leading cancer centres; Salzburg University Hospital treated its 1,000th Mobetron patient in August 2026. IntraOp describes Mobetron as the only electron ultra-high dose rate device approved for FLASH clinical trials. With Lausanne University Hospital (CHUV) it supported IMPulse, the first human dose-escalation study of single-fraction FLASH radiotherapy: 15 cutaneous melanoma metastases in 11 patients were treated at 22 to 28 Gy with no dose-limiting toxicities, published in Radiotherapy and Oncology in March 2026. IntraOp is privately held and based in Fremont, California; no funding details were found.","asOf":"2026-09-10","links":[{"label":"Official website","url":"https://intraop.com"},{"label":"About IntraOp","url":"https://intraop.com/intraop/"},{"label":"IMPulse FLASH trial completion with CHUV (March 2026)","url":"https://intraop.com/news-events/intraop-medical-announces-completion-of-pioneering-human-flash-radiotherapy-trial-and-publication-of-landmark-clinical-physics-results-with-lausanne-university-hospital-chuv/"},{"label":"News and events","url":"https://intraop.com/intraop/news-and-events-2/"}],"tags":[],"related":[],"cancers":["melanoma"],"sections":["radiation","surgery","devices"],"technologies":["flash-rt","imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["The caller's hint of Sunnyvale CA was not confirmed; the website and 2026 press release give 448 Kato Terrace, Fremont, CA. The site returns HTTP 403 to curl but loads via WebFetch. Founding year not stated (Mobetron introduced 1993). No funding, investors or ownership found; 'private-large' chosen because the company is a decades-old private manufacturer rather than a venture-stage startup. FDA clearance year for Mobetron not stated on fetched pages."],"hq":"Fremont, CA","country":"US","companyType":"devices","website":"https://intraop.com","stage":"private-large","investors":[],"funding":[]},"route":"/companies/intraop-medical/","neighbours":{"cancer":[{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"}],"section":[{"id":"devices","kind":"section","name":"Devices & Physical Therapies","route":"/fronts/devices/"},{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"},{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"electron-beam-therapy-systems","kind":"technology","name":"Electron beam therapy systems (linac electrons, total skin electron units, mobile electron IORT)","route":"/technologies/electron-beam-therapy-systems/"},{"id":"flash-rt","kind":"technology","name":"FLASH radiotherapy","route":"/technologies/flash-rt/"},{"id":"flash-research-accelerators","kind":"technology","name":"FLASH research accelerators (Oriatron, Mobetron FLASH, ProBeam FLASH)","route":"/technologies/flash-research-accelerators/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"},{"id":"intraoperative-radiotherapy","kind":"technology","name":"Intraoperative radiotherapy (IORT)","route":"/technologies/intraoperative-radiotherapy/"}]}}