{"entity":{"id":"insys-therapeutics","kind":"company","name":"Insys Therapeutics","aka":["INSYS Therapeutics Inc","Insys Therapeutics, Inc."],"tldr":"Insys Therapeutics was an Arizona company whose sublingual fentanyl spray for breakthrough cancer pain went through phase 3 trials; its marketing practices later led to criminal convictions and bankruptcy.","summary":"Insys Therapeutics, founded in 1990 and based in Chandler, Arizona, developed Subsys, a fentanyl sublingual spray approved for breakthrough pain in opioid-tolerant cancer patients, and a dronabinol oral solution. Its executives were convicted in 2019 over kickbacks to prescribers, and the company filed for bankruptcy the same year. Its phase 3 trials in cancer pain remain on ClinicalTrials.gov under Insys as lead sponsor. ClinicalTrials.gov also lists under Insys the earlier NeoPharm programmes it absorbed, including the interleukin-13 conjugated toxin IL13-PE38QQR (cintredekin besudotox) in malignant glioma (NCT00076986) and liposomal paclitaxel and docetaxel formulations.","asOf":"2026-09-11","wikipedia":"https://en.wikipedia.org/wiki/Insys_Therapeutics","links":[{"label":"Official website","url":"http://www.insysrx.com"},{"label":"ClinicalTrials.gov: trials led by INSYS Therapeutics Inc","url":"https://clinicaltrials.gov/search?lead=INSYS%20Therapeutics%20Inc"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q19903344"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["glioblastoma"],"sections":["supportive-care"],"technologies":["pain-management"],"targets":[],"drugs":["dronabinol"],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Chandler, AZ","country":"US","companyType":"pharma","website":"http://www.insysrx.com","founded":1990,"stage":"defunct","investors":[],"funding":[]},"route":"/companies/insys-therapeutics/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"section":[{"id":"supportive-care","kind":"section","name":"Supportive Care & Survivorship","route":"/fronts/supportive-care/"}],"technology":[{"id":"pain-management","kind":"technology","name":"Cancer pain management","route":"/technologies/pain-management/"}],"drug":[{"id":"dronabinol","kind":"drug","name":"Dronabinol","route":"/drugs/dronabinol/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}