{"entity":{"id":"idea-tr1-open-trials-inside-guidelines","kind":"idea","name":"Guidelines list the open trials at every decision point, updated monthly","aka":[],"tldr":"Treatment guidelines tell doctors what to do at each step but rarely which trials are open for that step. Adding a live, monthly-updated list to each decision node would put trials where doctors look.","summary":"NCCN, ESMO and national guidelines add a machine-updated 'open trials for this node' panel to each algorithm step, generated from registry data filtered by setting and line of therapy, with a link to slot availability. The static 'clinical trial participation is encouraged' footnote becomes actionable.","asOf":"2026-09-08","links":[{"label":"Bottleneck evidence (Trials enrol too few, too slowly): Unger et al., Systematic review of barriers to cancer trial participation (JNCI 2019)","url":"https://doi.org/10.1093/jnci/djy221"}],"tags":[],"related":["nccn","esmo-guidelines","clinicaltrials-gov"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["esmo"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":["b-trial-enrolment","b-knowledge-diffusion"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hypothesis":"Decision nodes with trial panels will have higher referral rates to the listed trials than nodes without, measured via referral-source tracking at trial sites.","rationale":"Guidelines are the most consulted documents in oncology practice; embedding trials there reaches every clinician without new software.","test":"One guideline body pilots panels for two cancers; sites of listed trials record referral source for a year.","maturity":"speculative","actor":"research","cost":"small","horizonYears":1},"route":"/ideas/idea-tr1-open-trials-inside-guidelines/","neighbours":{"collection":[{"id":"clinicaltrials-gov","kind":"collection","name":"ClinicalTrials.gov","route":"/collections/clinicaltrials-gov/"},{"id":"esmo-guidelines","kind":"collection","name":"ESMO Clinical Practice Guidelines & MCBS","route":"/collections/esmo-guidelines/"},{"id":"nccn","kind":"collection","name":"NCCN Guidelines","route":"/collections/nccn/"}],"institution":[{"id":"esmo","kind":"institution","name":"European Society for Medical Oncology (ESMO)","route":"/institutions/esmo/"}],"bottleneck":[{"id":"b-knowledge-diffusion","kind":"bottleneck","name":"Knowledge reaches practice too slowly","route":"/bottlenecks/b-knowledge-diffusion/"},{"id":"b-trial-enrolment","kind":"bottleneck","name":"Trials enrol too few, too slowly","route":"/bottlenecks/b-trial-enrolment/"}]}}