{"entity":{"id":"idea-moon-living-machine-readable-guidelines","kind":"idea","name":"Living, machine-readable guidelines pushed to the point of care in every country","aka":[],"tldr":"Cancer treatment guidance changes constantly and takes years to reach many clinics. Make guidelines live documents that software can read, updated as evidence arrives and adapted to what each country can afford.","summary":"Guidelines are published as prose, updated on annual cycles, and adapted slowly for resource-limited settings; diffusion of practice-changing evidence takes years. The proposal is a shared open format for computable guidelines (eligibility, options, evidence grades, resource tiers), a living update process triggered by trial results, and integration into electronic prescribing and decision support so that every treatment plan is checked against current, resource-appropriate guidance, with feedback on concordance by country and centre.","asOf":"2026-09-08","links":[{"label":"Bottleneck evidence (Knowledge reaches practice too slowly): Morris, Wooding & Grant, The answer is 17 years, what is the question (JRSM 2011)","url":"https://doi.org/10.1258/jrsm.2011.110180"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["asco","esmo"],"pathways":[],"terms":["standard-of-care"],"trials":[],"people":[],"bottlenecks":["b-knowledge-diffusion","b-global-access","b-care-fragmentation"],"keyPapers":["paper-morris-j-r-soc-med"],"journals":[],"dependsOn":[],"notes":[],"hypothesis":"Computable living guidelines cut the median time from practice-changing trial to routine use from years to months and raise guideline concordance in participating low- and middle-income centres.","rationale":"Knowledge diffusion fails at the last mile; software can carry the update to every prescriber, and resource tiering (as NCCN Harmonized Guidelines began) makes the guidance applicable.","test":"Implement for three cancers across twenty centres in five countries; measure time to adoption of new evidence and concordance before and after.","maturity":"early-clinical","actor":"data","cost":"medium","horizonYears":3},"route":"/ideas/idea-moon-living-machine-readable-guidelines/","neighbours":{"institution":[{"id":"asco","kind":"institution","name":"American Society of Clinical Oncology (ASCO)","route":"/institutions/asco/"},{"id":"esmo","kind":"institution","name":"European Society for Medical Oncology (ESMO)","route":"/institutions/esmo/"}],"term":[{"id":"standard-of-care","kind":"term","name":"Standard of care","route":"/terms/standard-of-care/"}],"bottleneck":[{"id":"b-care-fragmentation","kind":"bottleneck","name":"Fragmented care and guideline gaps","route":"/bottlenecks/b-care-fragmentation/"},{"id":"b-knowledge-diffusion","kind":"bottleneck","name":"Knowledge reaches practice too slowly","route":"/bottlenecks/b-knowledge-diffusion/"},{"id":"b-global-access","kind":"bottleneck","name":"Most of the world has almost no cancer care","route":"/bottlenecks/b-global-access/"}],"paper":[{"id":"paper-morris-j-r-soc-med","kind":"paper","name":"The answer is 17 years, what is the question: understanding time lags in translational research","route":"/key-papers/paper-morris-j-r-soc-med/"}]}}