{"entity":{"id":"idea-moon-global-open-trials-os","kind":"idea","name":"A global open trials operating system any hospital can plug into","aka":[],"tldr":"Build the shared software, legal templates and data standards that let any hospital in the world join a cancer trial in weeks instead of years, the way the internet let any computer join the network.","summary":"Trial start-up takes many months per site because every sponsor, country and hospital reinvents contracts, ethics submissions, data capture and monitoring. The proposal is an open-source, openly governed trials operating system: standard master agreements, a single global ethics dossier format accepted by participating regulators, e-consent and eligibility modules, mCODE-based data capture from electronic records, risk-based remote monitoring and open protocol templates, with certification of sites and a fund to connect hospitals in low- and middle-income countries.","asOf":"2026-09-08","links":[{"label":"Clinical Trials Transformation Initiative","url":"https://ctti-clinicaltrials.org/"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":["ai-trial-matching"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":["b-trial-enrolment","b-regulatory-fragmentation","b-trial-diversity"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hypothesis":"Sites on the operating system open trials in under 60 days at a fifth of current start-up cost, and the share of global trial enrolment from middle-income countries doubles within five years.","rationale":"Open standards and shared infrastructure transformed payments, logistics and the web; trials remain artisanal. Regulatory convergence (ICH, reliance pathways) makes a shared dossier plausible now.","test":"Deploy across 100 hospitals in ten countries with five sponsors; compare start-up time, cost per patient and enrolment diversity against matched conventional sites.","maturity":"speculative","actor":"engineering","cost":"large","horizonYears":5},"route":"/ideas/idea-moon-global-open-trials-os/","neighbours":{"technology":[{"id":"ai-trial-matching","kind":"technology","name":"AI trial matching & clinical decision support","route":"/technologies/ai-trial-matching/"}],"bottleneck":[{"id":"b-regulatory-fragmentation","kind":"bottleneck","name":"Regulatory divergence between regions","route":"/bottlenecks/b-regulatory-fragmentation/"},{"id":"b-trial-diversity","kind":"bottleneck","name":"Trials do not represent the people who get cancer","route":"/bottlenecks/b-trial-diversity/"},{"id":"b-trial-enrolment","kind":"bottleneck","name":"Trials enrol too few, too slowly","route":"/bottlenecks/b-trial-enrolment/"}]}}