{"entity":{"id":"idea-fund-trial-data-trust","kind":"idea","name":"A single oncology trial data trust with mandatory deposit within eighteen months","aka":[],"tldr":"Every cancer trial's anonymised patient-level data would go into one trusted repository within eighteen months of completion, with a single access committee, so researchers can re-analyse, pool and learn from trials that today stay locked up.","summary":"Consolidate the existing sharing platforms (Vivli, Project Data Sphere, YODA, ClinicalStudyDataRequest) into a single oncology data trust with a legal duty to deposit individual participant data, protocols and analysis code within eighteen months of primary completion for all trials whose results support a regulatory decision or that receive public funding. One independent access committee, standard data formats (CDISC), a secure analysis environment and a public catalogue. Trials in oncology already have among the highest voluntary sharing rates but access remains slow and fragmented, and negative or discontinued trials are rarely deposited at all.","asOf":"2026-09-08","links":[{"label":"Vivli","url":"https://vivli.org/"},{"label":"Project Data Sphere","url":"https://www.projectdatasphere.org/"},{"label":"YODA Project","url":"https://yoda.yale.edu/"}],"tags":[],"related":["clinicaltrials-gov","idea-fund-control-arm-commons","idea-fund-trial-biospecimen-commons","idea-fund-stalled-asset-registry"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["real-world-evidence"],"trials":[],"people":[],"bottlenecks":["b-ip-collaboration","b-negative-results","b-data-silos"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hypothesis":"Mandatory deposit raises the proportion of registration oncology trials with accessible individual participant data from a minority to above 80% within three years, and the median time from request to data access falls below sixty days.","rationale":"The EMA's clinical data publication policy and the ICMJE data-sharing statement requirement increased availability without harming sponsors; pooled analyses from shared data (for example Project Data Sphere control-arm analyses) have already produced prognostic tools and answered questions no single trial could.","test":"A group of funders and one regulator make deposit a condition of funding and approval for two years; measure deposit compliance, access time and the number of secondary analyses published.","maturity":"early-clinical","actor":"data","cost":"medium","horizonYears":3},"route":"/ideas/idea-fund-trial-data-trust/","neighbours":{"collection":[{"id":"clinicaltrials-gov","kind":"collection","name":"ClinicalTrials.gov","route":"/collections/clinicaltrials-gov/"}],"idea":[{"id":"idea-fund-trial-biospecimen-commons","kind":"idea","name":"A commons for leftover trial biospecimens with standard access for approved research","route":"/ideas/idea-fund-trial-biospecimen-commons/"},{"id":"idea-fund-federated-learning-consortium","kind":"idea","name":"A federated learning consortium of cancer centres that jointly own the models","route":"/ideas/idea-fund-federated-learning-consortium/"},{"id":"idea-fund-stalled-asset-registry","kind":"idea","name":"A public registry of stalled academic assets and shelved company compounds","route":"/ideas/idea-fund-stalled-asset-registry/"},{"id":"idea-fund-control-arm-commons","kind":"idea","name":"A shared library of pooled control arms to shrink and speed future trials","route":"/ideas/idea-fund-control-arm-commons/"},{"id":"idea-fund-antitrust-safe-harbour","kind":"idea","name":"An antitrust safe harbour for cross-company combination trials and data pooling","route":"/ideas/idea-fund-antitrust-safe-harbour/"},{"id":"idea-fund-phase-two-failure-reinsurance","kind":"idea","name":"Government reinsurance for phase 2 failures of first-in-class cancer drugs","route":"/ideas/idea-fund-phase-two-failure-reinsurance/"},{"id":"idea-fund-portable-patient-consent","kind":"idea","name":"Patient-held portable consent for reusing samples and data across studies","route":"/ideas/idea-fund-portable-patient-consent/"}],"term":[{"id":"real-world-evidence","kind":"term","name":"Real-world evidence","route":"/terms/real-world-evidence/"}],"bottleneck":[{"id":"b-data-silos","kind":"bottleneck","name":"Data silos","route":"/bottlenecks/b-data-silos/"},{"id":"b-negative-results","kind":"bottleneck","name":"Failures are hidden","route":"/bottlenecks/b-negative-results/"},{"id":"b-ip-collaboration","kind":"bottleneck","name":"Secrecy and intellectual property block collaboration","route":"/bottlenecks/b-ip-collaboration/"}]}}