{"entity":{"id":"idea-data-implementation-trials-programme","kind":"idea","name":"Randomised trials of how to spread proven cancer treatments, not just what works","aka":[],"tldr":"Fund proper trials of the methods used to get new evidence into practice (training, reminders, feedback, incentives), measured by whether patients actually receive the better treatment.","summary":"Implementation science in oncology is small and mostly observational. The proposal is a dedicated programme of cluster-randomised implementation trials, each testing strategies (audit and feedback, EHR defaults, champions, payment nudges) to accelerate uptake of a specific practice change, with structured-data outcomes and a common design so results generalise. NCI's Implementation Science programme is a base; the scale and randomisation are new.","asOf":"2026-09-08","links":[{"label":"Bottleneck evidence (Knowledge reaches practice too slowly): Morris, Wooding & Grant, The answer is 17 years, what is the question (JRSM 2011)","url":"https://doi.org/10.1258/jrsm.2011.110180"}],"tags":[],"related":[],"cancers":[],"sections":["ai-computation"],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["nci"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":["b-knowledge-diffusion","b-funding-allocation"],"keyPapers":["paper-morris-j-r-soc-med"],"journals":[],"dependsOn":[],"notes":[],"hypothesis":"A portfolio of implementation trials will identify strategies that halve the time to majority uptake for specific practice changes, and those strategies will transfer across at least some other practice changes.","rationale":"Cardiology's Get With The Guidelines and similar programmes showed that structured implementation measurably improves guideline adherence; oncology lacks equivalent evidence about what works.","test":"Fund five cluster-randomised implementation trials on current practice changes; report effect sizes and cost per additional patient receiving guideline-concordant care.","maturity":"early-clinical","actor":"research","cost":"medium","horizonYears":3},"route":"/ideas/idea-data-implementation-trials-programme/","neighbours":{"section":[{"id":"ai-computation","kind":"section","name":"AI & Computation","route":"/fronts/ai-computation/"}],"institution":[{"id":"nci","kind":"institution","name":"National Cancer Institute (NIH)","route":"/institutions/nci/"}],"bottleneck":[{"id":"b-funding-allocation","kind":"bottleneck","name":"Funding follows fashion, not burden","route":"/bottlenecks/b-funding-allocation/"},{"id":"b-knowledge-diffusion","kind":"bottleneck","name":"Knowledge reaches practice too slowly","route":"/bottlenecks/b-knowledge-diffusion/"}],"paper":[{"id":"paper-morris-j-r-soc-med","kind":"paper","name":"The answer is 17 years, what is the question: understanding time lags in translational research","route":"/key-papers/paper-morris-j-r-soc-med/"}]}}