{"entity":{"id":"icon-plc","kind":"company","name":"ICON plc","aka":[],"tldr":"ICON is an Irish CRO (including PRA Health Sciences) with a large oncology franchise and an imaging core lab.","summary":"ICON plc, based in Dublin and listed as ICLR, is an Irish contract research organisation, including the former PRA Health Sciences, with a large oncology franchise and an imaging core laboratory. It offers full-service trials, central review of medical imaging and site networks. OnCo links it to contract research organisations and to imaging core labs and central review. Whether centralised imaging review, which its core lab provides, remains the standard as AI-based response assessment matures is the open question for that part of its business. The CRO technology page carries the wider picture.","asOf":"2026-09-08","wikipedia":"https://en.wikipedia.org/wiki/ICON_PLC","links":[{"label":"Official website","url":"https://www.iconplc.com"}],"tags":["supporting"],"related":[],"cancers":[],"sections":["ai-computation","imaging"],"technologies":["contract-research-organisations","imaging-core-labs"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct05322590","nct07647328"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Dublin","country":"IE","companyType":"cro-services","website":"https://www.iconplc.com","ticker":"ICLR","investors":[],"funding":[]},"route":"/companies/icon-plc/","neighbours":{"section":[{"id":"ai-computation","kind":"section","name":"AI & Computation","route":"/fronts/ai-computation/"},{"id":"imaging","kind":"section","name":"Imaging","route":"/fronts/imaging/"}],"technology":[{"id":"contract-research-organisations","kind":"technology","name":"Contract research organisations (CROs)","route":"/technologies/contract-research-organisations/"},{"id":"imaging-core-labs","kind":"technology","name":"Imaging core labs and central review","route":"/technologies/imaging-core-labs/"}],"trial":[{"id":"nct07647328","kind":"trial","name":"A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer","route":"/trials/nct07647328/"},{"id":"nct05032040","kind":"trial","name":"A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies","route":"/trials/nct05032040/"},{"id":"nct05322590","kind":"trial","name":"BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma","route":"/trials/nct05322590/"}]}}