{"entity":{"id":"iah0968","kind":"drug","name":"IAH0968","aka":[],"tldr":"IAH0968 is an experimental small-molecule drug from SUNHO（China）BioPharmaceutical CO. in phase 3 trials for gastric & gastro-oesophageal junction cancer, aimed at HER2.","summary":"IAH0968 is a small-molecule drug developed by SUNHO（China）BioPharmaceutical CO.. Its target is HER2 (the sponsor names HER2). ClinicalTrials.gov describes the intervention as: Experimental：IAH0968 15 mg/kg on Day 1 of each 3-week cycle as an IV infusion. Drug: Oxaliplatin 130 mg/m\\^2 on Day 1 of each 3-week cycle over 2 hours as an IV infusion, administered as part of CAPOX chemotherapy regimen. Drug: Capecitabin. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, including the phase 3 study NCT06504732 (To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer), in gastric & gastro-oesophageal junction cancer. The largest, NCT06504732, plans to enrol 574 participants with primary completion expected 2028-07. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.","status":"phase-3","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov: trials of IAH0968","url":"https://clinicaltrials.gov/search?intr=IAH0968"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["gastric"],"sections":[],"technologies":[],"targets":["her2"],"drugs":[],"companies":["hutchmed"],"institutions":[],"pathways":[],"terms":[],"trials":["nct06504732"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor pipeline pages)","editedOn":"2026-09-11"},"modality":"monoclonal antibody (anti-HER2, per the sponsor's pipeline page; registered as a drug on ClinicalTrials.gov)","mechanism":"Small-molecule drug directed at HER2, as stated in the ClinicalTrials.gov intervention record; the detailed mechanism is not stated.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/iah0968/","neighbours":{"cancer":[{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"}],"target":[{"id":"her2","kind":"target","name":"HER2","route":"/targets/her2/"}],"company":[{"id":"hutchmed","kind":"company","name":"Hutchmed","route":"/companies/hutchmed/"},{"id":"sunho-biopharmaceutical","kind":"company","name":"SunHo Biopharmaceutical","route":"/companies/sunho-biopharmaceutical/"}],"trial":[{"id":"nct06504732","kind":"trial","name":"To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer","route":"/trials/nct06504732/"}]}}