{"entity":{"id":"humanitas","kind":"institution","name":"IRCCS Humanitas Research Hospital","aka":["Humanitas Cancer Center","Istituto Clinico Humanitas"],"tldr":"A Milan research hospital known for Alberto Mantovani's work on tumour-associated macrophages and for stereotactic radiotherapy and liver cancer trials.","summary":"Humanitas Research Hospital, founded in 1996 in Rozzano, is a private IRCCS teaching hospital with its own Humanitas University. Alberto Mantovani, its scientific director, established the concept of cancer-related inflammation and the role of tumour-associated macrophages, complement and pentraxin 3 in tumour progression. The Humanitas Cancer Center under Armando Santoro has been a major site for hepatocellular carcinoma and biliary cancer trials, including with Lorenza Rimassa, and Marta Scorsetti's radiotherapy department is a leader in stereotactic body radiotherapy for oligometastatic disease. The hospital also runs haematology, thoracic and colorectal surgery and an early-phase unit, and holds OECI accreditation.","asOf":"2026-09-09","links":[{"label":"Homepage","url":"https://www.humanitas.net"},{"label":"Cancer Center","url":"https://www.humanitas.net/cancer-center/"}],"tags":[],"related":[],"cancers":["hcc","cholangiocarcinoma","dlbcl","nsclc"],"sections":["radiation","immunotherapy"],"technologies":["sbrt","checkpoint-inhibitor","car-nk-macrophage","imrt-igrt"],"targets":[],"drugs":["durvalumab","atezolizumab"],"companies":[],"institutions":["oeci"],"pathways":[],"terms":["oligometastatic","cold-vs-hot"],"trials":[],"people":["simona-sancini","armando-santoro","domenica-lorusso","riccardo-bui"],"bottlenecks":["b-tme-immunosuppression"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Rozzano (Milan)","country":"IT","lat":45.399,"lng":9.167,"institutionType":"hospital","website":"https://www.humanitas.net","university":"Humanitas University","programs":["Tumour-associated macrophages and innate immunity","Hepatobiliary oncology trials","Stereotactic body radiotherapy","Haematology","Early-phase trials"]},"route":"/institutions/humanitas/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"section":[{"id":"immunotherapy","kind":"section","name":"Immunotherapy","route":"/fronts/immunotherapy/"},{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"}],"technology":[{"id":"car-nk-macrophage","kind":"technology","name":"CAR-NK & CAR-macrophage","route":"/technologies/car-nk-macrophage/"},{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"},{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"drug":[{"id":"atezolizumab","kind":"drug","name":"Atezolizumab","route":"/drugs/atezolizumab/"},{"id":"durvalumab","kind":"drug","name":"Durvalumab","route":"/drugs/durvalumab/"}],"institution":[{"id":"policlinico-san-matteo","kind":"institution","name":"Fondazione IRCCS Policlinico San Matteo","route":"/institutions/policlinico-san-matteo/"},{"id":"fondazione-poliambulanza","kind":"institution","name":"Fondazione Poliambulanza","route":"/institutions/fondazione-poliambulanza/"},{"id":"oeci","kind":"institution","name":"Organisation of European Cancer Institutes","route":"/institutions/oeci/"}],"term":[{"id":"cold-vs-hot","kind":"term","name":"Hot vs cold tumours","route":"/terms/cold-vs-hot/"},{"id":"oligometastatic","kind":"term","name":"Oligometastatic disease","route":"/terms/oligometastatic/"}],"person":[{"id":"armando-santoro","kind":"person","name":"Armando Santoro","route":"/people/armando-santoro/"},{"id":"domenica-lorusso","kind":"person","name":"Domenica Lorusso","route":"/people/domenica-lorusso/"},{"id":"riccardo-bui","kind":"person","name":"Riccardo Bui","route":"/people/riccardo-bui/"},{"id":"simona-sancini","kind":"person","name":"Simona Sancini","route":"/people/simona-sancini/"}],"bottleneck":[{"id":"b-tme-immunosuppression","kind":"bottleneck","name":"Cold tumours and the immunosuppressive microenvironment","route":"/bottlenecks/b-tme-immunosuppression/"}],"paper":[{"id":"paper-balkwill-mantovani-inflammation-virchow-lancet-2001","kind":"paper","name":"Balkwill and Mantovani 2001: inflammation and cancer, back to Virchow?","route":"/key-papers/paper-balkwill-mantovani-inflammation-virchow-lancet-2001/"}]}}