{"entity":{"id":"hubert-serve","kind":"person","name":"Hubert Serve","aka":[],"tldr":"Leukaemia specialist heading haematology and oncology at University Hospital Frankfurt and co-author of the pivotal RATIFY midostaurin trial.","summary":"Hubert Serve is Director of the Department of Internal Medicine 2 (Hematology/Oncology) at University Hospital Frankfurt and a member of the UCT Frankfurt directorate. His research on FLT3 signalling in acute myeloid leukaemia contributed to the development of FLT3 inhibitors, including the international RATIFY trial of midostaurin published in the New England Journal of Medicine in 2017.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://www.uct-frankfurt.de/ueber-uns/direktorium/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Serve+H%5BAuthor%5D"}],"tags":["leadership","clinician-scientist","leukaemia","haematology"],"related":[],"cancers":["aml"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["uct-frankfurt"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Director, Department of Internal Medicine 2 (Hematology/Oncology)","institutionId":"uct-frankfurt","specialisms":["Acute myeloid leukaemia","Haematology","Targeted therapy"],"profiles":[{"label":"Institution profile","url":"https://www.uct-frankfurt.de/ueber-uns/direktorium/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Serve+H%5BAuthor%5D"}],"papers":[{"title":"Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation","journal":"New England Journal of Medicine","year":2017,"url":"https://doi.org/10.1056/NEJMoa1614359","doi":"10.1056/NEJMoa1614359"}],"orcid":"0000-0001-8472-5516"},"route":"/people/hubert-serve/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"}],"institution":[{"id":"uct-frankfurt","kind":"institution","name":"University Cancer Center Frankfurt (UCT)","route":"/institutions/uct-frankfurt/"}]}}