{"entity":{"id":"hu-xichun","kind":"person","name":"Xichun Hu","aka":[],"tldr":"A breast medical oncologist who has led Chinese trials of chemotherapy, CDK4/6 inhibitors, and ADCs in advanced breast cancer.","summary":"Xichun Hu is Professor of Medical Oncology and Chief of the Department of Breast and Urologic Medical Oncology at Fudan University Shanghai Cancer Center. He has led Chinese trials of chemotherapy, CDK4/6 inhibitors and antibody-drug conjugates in advanced breast cancer, serving as principal investigator on studies of platinum-based chemotherapy in triple-negative disease, dalpiciclib, and new conjugates including sacituzumab tirumotecan and trastuzumab rezetecan. His publications include the CBCSG006 trial comparing cisplatin plus gemcitabine with paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer. His interests are breast cancer, chemotherapy, antibody-drug conjugates and clinical trials.","asOf":"2026-09-08","links":[{"label":"Fudan University Shanghai Cancer Center","url":"https://www.shca.org.cn"},{"label":"PubMed author search","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Hu%20X%5BAuthor%5D%20Fudan%20breast%20cancer"}],"tags":[],"related":[],"cancers":["tnbc","breast-hr-positive"],"sections":[],"technologies":["platinum"],"targets":[],"drugs":["sacituzumab-tirumotecan","trastuzumab-rezetecan"],"companies":[],"institutions":["fuscc"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Professor of Medical Oncology; Chief, Department of Breast and Urologic Medical Oncology, Fudan University Shanghai Cancer Center","institutionId":"fuscc","specialisms":["Breast cancer","Chemotherapy","Antibody-drug conjugates","Clinical trials"],"profiles":[{"label":"Fudan University Shanghai Cancer Center","url":"https://www.shca.org.cn"},{"label":"PubMed author search","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Hu%20X%5BAuthor%5D%20Fudan%20breast%20cancer"}],"papers":[{"title":"Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (CBCSG006)","journal":"Lancet Oncology","year":2015,"doi":"10.1016/S1470-2045(15)70064-1"},{"title":"DESTINY-Breast06: trastuzumab deruxtecan before any chemotherapy in hormone-receptor-positive, HER2-low or ultralow breast cancer","journal":"New England Journal of Medicine","year":2024,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DESTINY-Breast06+trastuzumab+deruxtecan+HER2-low+chemotherapy-naive"}]},"route":"/people/hu-xichun/","neighbours":{"cancer":[{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"technology":[{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"sacituzumab-tirumotecan","kind":"drug","name":"Sacituzumab tirumotecan","route":"/drugs/sacituzumab-tirumotecan/"},{"id":"trastuzumab-rezetecan","kind":"drug","name":"Trastuzumab rezetecan","route":"/drugs/trastuzumab-rezetecan/"}],"institution":[{"id":"fuscc","kind":"institution","name":"Fudan University Shanghai Cancer Center","route":"/institutions/fuscc/"}],"paper":[{"id":"paper-destiny-breast06-nejm-2024","kind":"paper","name":"DESTINY-Breast06: trastuzumab deruxtecan before any chemotherapy in hormone-receptor-positive, HER2-low or ultralow breast cancer","route":"/key-papers/paper-destiny-breast06-nejm-2024/"}]}}