{"entity":{"id":"hepatectomy","kind":"term","name":"Hepatectomy (liver resection)","aka":["liver resection","partial hepatectomy","hemihepatectomy","hepatic resection","metastasectomy"],"tldr":"Cutting out the part of the liver containing tumour. The liver regrows, so up to 70% can be removed if what remains is healthy.","summary":"Used for hepatocellular carcinoma in patients with preserved liver function (Child-Pugh A, no portal hypertension), for cholangiocarcinoma, and for colorectal liver metastases, where resection gives 5-year survival of 40-50% and is the only curative option. Portal vein embolisation or two-stage hepatectomy grows the future liver remnant before surgery; ablation handles small lesions. Anatomical segments (Couinaud) define the resection; a margin of even 1 mm is acceptable in metastases.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/Hepatectomy","links":[{"label":"Wikipedia","url":"https://en.wikipedia.org/wiki/Hepatectomy"},{"label":"NICE NG151: colorectal cancer, recommendations","url":"https://www.nice.org.uk/guidance/ng151/chapter/Recommendations"},{"label":"Bowel Cancer UK: treating advanced bowel cancer","url":"https://www.bowelcanceruk.org.uk/about-bowel-cancer/advanced-bowel-cancer/treating-advanced-bowel-cancer/"},{"label":"Macmillan: treatment for advanced bowel cancer","url":"https://www.macmillan.org.uk/cancer-information-and-support/bowel-cancer/treatment-for-advanced-bowel-cancer"}],"tags":[],"related":["child-pugh","resection-margins","downstaging"],"cancers":["hcc","cholangiocarcinoma","colorectal"],"sections":["surgery"],"technologies":["thermal-ablation"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Colorectal liver metastases: NICE NG151 says to consider resection, either simultaneous or sequential, after discussion by a multidisciplinary team with expertise in resection of disease in all involved sites; to consider perioperative systemic anticancer therapy if liver resection is a suitable treatment; and to consider chemotherapy with local ablative techniques for liver metastases that are unsuitable for resection after discussion by a specialist multidisciplinary team."],"category":"Procedures"},"route":"/terms/hepatectomy/","neighbours":{"term":[{"id":"child-pugh","kind":"term","name":"Child-Pugh score","route":"/terms/child-pugh/"},{"id":"downstaging","kind":"term","name":"Downstaging and conversion therapy","route":"/terms/downstaging/"},{"id":"liver-directed-therapy","kind":"term","name":"Liver-directed therapy (TACE, TARE, HAI, ablation)","route":"/terms/liver-directed-therapy/"},{"id":"radical-cholecystectomy","kind":"term","name":"Radical (extended) cholecystectomy","route":"/terms/radical-cholecystectomy/"},{"id":"resection-margins","kind":"term","name":"Resection margins (R0 / R1 / R2)","route":"/terms/resection-margins/"},{"id":"segment-ivb-v-resection","kind":"term","name":"Segment IVb and V liver resection (versus wedge resection)","route":"/terms/segment-ivb-v-resection/"}],"cancer":[{"id":"advanced-small-bowel-adenocarcinoma","kind":"cancer","name":"Advanced and metastatic small bowel adenocarcinoma","route":"/cancers/advanced-small-bowel-adenocarcinoma/"},{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"hcc-early","kind":"cancer","name":"Early hepatocellular carcinoma (BCLC 0 and A)","route":"/cancers/hcc-early/"},{"id":"extrahepatic-cholangiocarcinoma","kind":"cancer","name":"Extrahepatic cholangiocarcinoma (perihilar and distal)","route":"/cancers/extrahepatic-cholangiocarcinoma/"},{"id":"gallbladder","kind":"cancer","name":"Gallbladder cancer","route":"/cancers/gallbladder/"},{"id":"grade-3-net","kind":"cancer","name":"Grade 3 well-differentiated neuroendocrine tumour","route":"/cancers/grade-3-net/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"intrahepatic-cholangiocarcinoma","kind":"cancer","name":"Intrahepatic cholangiocarcinoma","route":"/cancers/intrahepatic-cholangiocarcinoma/"},{"id":"pancreatic-net","kind":"cancer","name":"Pancreatic neuroendocrine tumours","route":"/cancers/pancreatic-net/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"},{"id":"small-intestinal-net","kind":"cancer","name":"Small intestinal neuroendocrine tumours","route":"/cancers/small-intestinal-net/"}],"section":[{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"gallbladder-cancer-surgery","kind":"technology","name":"Surgery for gallbladder cancer: simple versus radical cholecystectomy, re-resection and lymphadenectomy","route":"/technologies/gallbladder-cancer-surgery/"},{"id":"thermal-ablation","kind":"technology","name":"Thermal ablation (RFA, microwave, cryo)","route":"/technologies/thermal-ablation/"}],"trial":[{"id":"cairo5","kind":"trial","name":"CAIRO5","route":"/trials/cairo5/"},{"id":"nct06037980","kind":"trial","name":"CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence","route":"/trials/nct06037980/"},{"id":"clocc","kind":"trial","name":"CLOCC","route":"/trials/clocc/"},{"id":"eortc-40983","kind":"trial","name":"EORTC 40983","route":"/trials/eortc-40983/"},{"id":"neogb","kind":"trial","name":"NEOGB","route":"/trials/neogb/"},{"id":"new-epoc","kind":"trial","name":"New EPOC","route":"/trials/new-epoc/"},{"id":"opt-in","kind":"trial","name":"OPT-IN (EA2197)","route":"/trials/opt-in/"}],"institution":[{"id":"addenbrookes-cambridge","kind":"institution","name":"Addenbrooke's Hospital, Cambridge University Hospitals","route":"/institutions/addenbrookes-cambridge/"},{"id":"belfast-trust-hpb","kind":"institution","name":"Belfast Health and Social Care Trust HPB service","route":"/institutions/belfast-trust-hpb/"},{"id":"derriford-plymouth","kind":"institution","name":"Derriford Hospital, University Hospitals Plymouth","route":"/institutions/derriford-plymouth/"},{"id":"glasgow-royal-infirmary","kind":"institution","name":"Glasgow Royal Infirmary","route":"/institutions/glasgow-royal-infirmary/"},{"id":"kings-college-hospital-london","kind":"institution","name":"King's College Hospital, London","route":"/institutions/kings-college-hospital-london/"},{"id":"liverpool-hpb-centre","kind":"institution","name":"Liverpool University Hospitals HPB centre (Aintree)","route":"/institutions/liverpool-hpb-centre/"},{"id":"manchester-royal-infirmary","kind":"institution","name":"Manchester Royal Infirmary HPB Unit","route":"/institutions/manchester-royal-infirmary/"},{"id":"morriston-swansea","kind":"institution","name":"Morriston Hospital, Swansea","route":"/institutions/morriston-swansea/"},{"id":"royal-infirmary-edinburgh","kind":"institution","name":"Royal Infirmary of Edinburgh","route":"/institutions/royal-infirmary-edinburgh/"},{"id":"university-hospital-wales-cardiff","kind":"institution","name":"University Hospital of Wales, Cardiff","route":"/institutions/university-hospital-wales-cardiff/"}],"person":[{"id":"hassan-malik","kind":"person","name":"Hassan Malik","route":"/people/hassan-malik/"},{"id":"fan-jia","kind":"person","name":"Jia Fan","route":"/people/fan-jia/"}]}}