{"entity":{"id":"hashim-ahmed","kind":"person","name":"Hashim U. Ahmed","aka":[],"tldr":"Led PROMIS, the trial that showed MRI can safely spare a quarter of men from prostate biopsy.","summary":"Hashim Ahmed (Imperial College London) was chief investigator of PROMIS, which showed multiparametric MRI has far higher sensitivity for clinically significant prostate cancer than TRUS biopsy and could allow 27% of men to avoid biopsy altogether. He leads focal therapy trials of HIFU and cryotherapy and the PART and CHRONOS studies comparing focal and radical treatment.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ahmed%20HU%5BAuthor%5D%20prostate%20PROMIS%20OR%20focal"}],"tags":["prostate","imaging","focal-therapy"],"related":[],"cancers":["prostate"],"sections":[],"technologies":["mri","hifu-histotripsy"],"targets":[],"drugs":[],"companies":[],"institutions":["imperial-cancer-centre"],"pathways":[],"terms":[],"trials":["precision-mri"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Chair of Urology, Imperial College London","institutionId":"imperial-cancer-centre","specialisms":["Prostate cancer diagnostics","Focal therapy","HIFU","Diagnostic trials"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ahmed%20HU%5BAuthor%5D%20prostate%20PROMIS%20OR%20focal"}],"papers":[{"title":"Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS)","journal":"Lancet","year":2017,"doi":"10.1016/S0140-6736(16)32401-1"},{"title":"Focal therapy for localised prostate cancer: a phase I/II trial","journal":"Lancet Oncology","year":2012,"doi":"10.1016/S1470-2045(12)70121-3"}],"orcid":"0000-0003-1674-6723"},"route":"/people/hashim-ahmed/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"technology":[{"id":"hifu-histotripsy","kind":"technology","name":"Focused ultrasound & histotripsy","route":"/technologies/hifu-histotripsy/"},{"id":"mri","kind":"technology","name":"MRI","route":"/technologies/mri/"}],"institution":[{"id":"imperial-cancer-centre","kind":"institution","name":"Imperial College Healthcare NHS Trust / Imperial College London Cancer Research","route":"/institutions/imperial-cancer-centre/"}],"trial":[{"id":"precision-mri","kind":"trial","name":"PRECISION","route":"/trials/precision-mri/"},{"id":"promis","kind":"trial","name":"PROMIS","route":"/trials/promis/"},{"id":"transform-prostate","kind":"trial","name":"TRANSFORM","route":"/trials/transform-prostate/"}],"person":[{"id":"caroline-moore","kind":"person","name":"Caroline Moore","route":"/people/caroline-moore/"},{"id":"rakesh-heer","kind":"person","name":"Rakesh Heer","route":"/people/rakesh-heer/"}]}}