{"entity":{"id":"harlan-krumholz","kind":"person","name":"Harlan M. Krumholz","aka":[],"tldr":"Yale outcomes researcher who founded and leads the YODA Project for independent access to clinical trial data.","summary":"Harlan M. Krumholz is Principal Investigator of the Yale University Open Data Access (YODA) Project, which provides independent researchers with access to participant-level clinical trial data from industry partners, including many oncology trials. A cardiologist and Harold H. Hines Jr. Professor of Medicine at Yale, he is a leading advocate for open science and research transparency.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://yoda.yale.edu/about/leadership-contact-information/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Krumholz+HM%5BAuthor%5D"}],"tags":["leadership","data sharing","research transparency"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["yoda-project"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["nature","nature-medicine"],"dependsOn":[],"notes":[],"role":"Principal Investigator","institutionId":"yoda-project","specialisms":["Clinical trial data sharing","Outcomes research","Cardiology","Research transparency"],"profiles":[{"label":"Institution profile","url":"https://yoda.yale.edu/about/leadership-contact-information/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Krumholz+HM%5BAuthor%5D"}],"papers":[{"title":"The mutational constraint spectrum quantified from variation in 141,456 humans","journal":"Nature","year":2020,"url":"https://doi.org/10.1038/s41586-020-2308-7","doi":"10.1038/s41586-020-2308-7","note":"Europe PMC author record matched by affiliation"},{"title":"Extrapulmonary manifestations of COVID-19","journal":"Nat Med","year":2020,"url":"https://doi.org/10.1038/s41591-020-0968-3","doi":"10.1038/s41591-020-0968-3","note":"Europe PMC author record matched by affiliation"},{"title":"COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review","journal":"J Am Coll Cardiol","year":2020,"url":"https://doi.org/10.1016/j.jacc.2020.04.031","doi":"10.1016/j.jacc.2020.04.031","note":"Europe PMC author record matched by affiliation"}],"orcid":"0000-0003-2046-127X"},"route":"/people/harlan-krumholz/","neighbours":{"institution":[{"id":"yoda-project","kind":"institution","name":"Yale University Open Data Access (YODA) Project","route":"/institutions/yoda-project/"}],"journal":[{"id":"nature","kind":"journal","name":"Nature","route":"/journals/nature/"},{"id":"nature-medicine","kind":"journal","name":"Nature Medicine","route":"/journals/nature-medicine/"}]}}