{"entity":{"id":"gastrectomy","kind":"term","name":"Gastrectomy","aka":["total gastrectomy","subtotal gastrectomy","gastrectomies"],"tldr":"Removing part (subtotal) or all (total) of the stomach for stomach cancer, with the bowel joined to what remains.","summary":"Curative surgery for localised gastric cancer, combined with D2 lymphadenectomy and perioperative FLOT chemotherapy in the West or adjuvant chemotherapy in East Asia, where screening finds earlier disease and endoscopic resection can cure tumours confined to the mucosa. Laparoscopic and robotic approaches are standard in Korea and Japan (KLASS, JCOG trials). Consequences include small-meal eating, dumping, vitamin B12 deficiency and weight loss, hence the drive to avoid palliative gastrectomy in metastatic disease.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/Gastrectomy","links":[{"label":"Wikipedia","url":"https://en.wikipedia.org/wiki/Gastrectomy"}],"tags":[],"related":["lymphadenectomy","endoscopic-resection","flot"],"cancers":["gastric","early-gastric-cancer","esophageal"],"sections":["surgery"],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"category":"Procedures"},"route":"/terms/gastrectomy/","neighbours":{"term":[{"id":"flot-term","kind":"term","name":"FLOT regimen (perioperative chemotherapy for gastric cancer)","route":"/terms/flot-term/"},{"id":"gej","kind":"term","name":"Gastro-oesophageal junction (GEJ)","route":"/terms/gej/"},{"id":"lymphadenectomy","kind":"term","name":"Lymphadenectomy (lymph node dissection)","route":"/terms/lymphadenectomy/"}],"technology":[{"id":"endoscopic-resection","kind":"technology","name":"Endoscopic resection (EMR / ESD)","route":"/technologies/endoscopic-resection/"}],"drug":[{"id":"flot","kind":"drug","name":"FLOT (5-FU, leucovorin, oxaliplatin, docetaxel)","route":"/drugs/flot/"}],"cancer":[{"id":"early-gastric-cancer","kind":"cancer","name":"Early gastric cancer","route":"/cancers/early-gastric-cancer/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"gastric-her2-positive","kind":"cancer","name":"HER2-positive gastric cancer","route":"/cancers/gastric-her2-positive/"},{"id":"gastric-msi-high","kind":"cancer","name":"Microsatellite-unstable (MSI-high) gastric cancer","route":"/cancers/gastric-msi-high/"},{"id":"esophageal","kind":"cancer","name":"Oesophageal cancer","route":"/cancers/esophageal/"}],"section":[{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"person":[{"id":"mitsuru-sasako","kind":"person","name":"Mitsuru Sasako","route":"/people/mitsuru-sasako/"}]}}