{"entity":{"id":"freddie-hamdy","kind":"person","name":"Freddie C. Hamdy","aka":[],"tldr":"Led ProtecT, the trial that showed monitoring, surgery and radiotherapy give equally low prostate cancer death rates at 15 years.","summary":"Freddie Hamdy was chief investigator of ProtecT, the UK randomised trial of active monitoring, prostatectomy and radiotherapy for PSA-detected localised prostate cancer, whose 10- and 15-year results showed very low and similar mortality across arms and made active surveillance a mainstream choice. He also co-led the CAP screening trial. He leads urological research in Oxford.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Hamdy%20FC%5BAuthor%5D%20ProtecT"}],"tags":["prostate","surgery","active-surveillance"],"related":[],"cancers":["prostate"],"sections":[],"technologies":["robotic-surgery"],"targets":[],"drugs":[],"companies":[],"institutions":["oxford-cancer"],"pathways":[],"terms":[],"trials":["protect"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Nuffield Professor of Surgery, University of Oxford","institutionId":"oxford-cancer","specialisms":["Prostate cancer","Active surveillance","Urological surgery","Screening"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Hamdy%20FC%5BAuthor%5D%20ProtecT"}],"papers":[{"title":"10-year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer (ProtecT)","journal":"NEJM","year":2016,"doi":"10.1056/NEJMoa1606220"},{"title":"Fifteen-year outcomes after monitoring, surgery, or radiotherapy for prostate cancer","journal":"NEJM","year":2023,"doi":"10.1056/NEJMoa2214122"}],"orcid":"0000-0003-2627-2154"},"route":"/people/freddie-hamdy/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"technology":[{"id":"robotic-surgery","kind":"technology","name":"Robotic & minimally invasive surgery","route":"/technologies/robotic-surgery/"}],"institution":[{"id":"oxford-cancer","kind":"institution","name":"Oxford Cancer (Oxford University Hospitals and University of Oxford)","route":"/institutions/oxford-cancer/"}],"trial":[{"id":"protect","kind":"trial","name":"ProtecT","route":"/trials/protect/"}],"person":[{"id":"jenny-donovan","kind":"person","name":"Jenny Donovan","route":"/people/jenny-donovan/"}]}}