{"entity":{"id":"exact-sciences","kind":"company","name":"Exact Sciences (Abbott)","aka":[],"tldr":"Exact Sciences makes Cologuard and Oncotype DX and is launching Cancerguard MCED and Oncodetect MRD; it is being acquired by Abbott for $21B.","summary":"Exact Sciences, based in Madison, Wisconsin, makes Cologuard and Oncotype DX and is launching the Cancerguard multi-cancer early detection test and the Oncodetect residual disease test; Abbott is acquiring it for 21 billion dollars. Its products span Cologuard Plus for stool-based colorectal screening, Oncotype DX for breast cancer recurrence risk, Oncodetect for MRD and Cancerguard, offered as a laboratory-developed test from 2025. OnCo links it to colorectal and HR-positive breast cancer, to MRD testing and multi-cancer early detection, to the early detection roadmap from organ screening to blood tests, and to Abbott Laboratories. Whether the Abbott deal turns a screening franchise into a broader diagnostics platform is the open question. Each product has its own page.","asOf":"2026-09-04","links":[{"label":"Official website","url":"https://www.exactsciences.com"}],"tags":[],"related":[],"cancers":[],"sections":["diagnostics","early-detection"],"technologies":[],"targets":[],"drugs":["oncotype-dx"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Madison, WI","country":"US","companyType":"diagnostics","website":"https://www.exactsciences.com","investors":[],"funding":[]},"route":"/companies/exact-sciences/","neighbours":{"section":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"drug":[{"id":"cancerguard","kind":"drug","name":"Cancerguard","route":"/drugs/cancerguard/"},{"id":"cologuard","kind":"drug","name":"Cologuard","route":"/drugs/cologuard/"},{"id":"cologuard-plus","kind":"drug","name":"Cologuard Plus","route":"/drugs/cologuard-plus/"},{"id":"oncodetect","kind":"drug","name":"Oncodetect","route":"/drugs/oncodetect/"},{"id":"oncotype-dx","kind":"drug","name":"Oncotype DX","route":"/drugs/oncotype-dx/"}],"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"}],"paper":[{"id":"paper-imperiale-multitarget-stool-dna-screening-nejm-2014","kind":"paper","name":"Multitarget stool DNA testing for colorectal-cancer screening","route":"/key-papers/paper-imperiale-multitarget-stool-dna-screening-nejm-2014/"}],"technology":[{"id":"mrd-testing","kind":"technology","name":"MRD / molecular residual disease testing","route":"/technologies/mrd-testing/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"},{"id":"multitarget-stool-rna-test","kind":"technology","name":"Multitarget stool RNA test (ColoSense)","route":"/technologies/multitarget-stool-rna-test/"}],"roadmap":[{"id":"ctdna-tests","kind":"roadmap","name":"ctDNA tests roadmap: from a curiosity in plasma to blood tests that decide treatment","route":"/roadmaps/ctdna-tests/"},{"id":"early-detection-roadmap","kind":"roadmap","name":"Early detection roadmap: organ screening → blood tests for many cancers","route":"/roadmaps/early-detection-roadmap/"}],"bottleneck":[{"id":"b-early-detection","kind":"bottleneck","name":"The hardest cancers are found late","route":"/bottlenecks/b-early-detection/"}],"trial":[{"id":"nct06850623","kind":"trial","name":"Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer","route":"/trials/nct06850623/"},{"id":"blue-c","kind":"trial","name":"BLUE-C","route":"/trials/blue-c/"},{"id":"deep-c","kind":"trial","name":"DeeP-C","route":"/trials/deep-c/"}],"company":[{"id":"abbott","kind":"company","name":"Abbott Laboratories","route":"/companies/abbott/"}]}}