{"entity":{"id":"erin-oshea","kind":"person","name":"Erin K. O'Shea","aka":[],"tldr":"Systems biologist who has led the Howard Hughes Medical Institute, a major funder of US biomedical and cancer research, since 2016.","summary":"Erin K. O'Shea is President of the Howard Hughes Medical Institute (HHMI), the largest private funder of academic biomedical research in the United States, whose investigators include many leading cancer biologists. Previously HHMI's Chief Scientific Officer and a Harvard professor, her research addressed signalling and gene regulatory networks in yeast and cyanobacteria.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=O%27Shea+EK%5BAuthor%5D"}],"tags":["leadership","research funding","systems biology"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["hhmi"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["nature","science"],"dependsOn":[],"notes":[],"role":"President","institutionId":"hhmi","specialisms":["Systems biology","Gene regulation","Research funding leadership"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=O%27Shea+EK%5BAuthor%5D"}],"papers":[{"title":"Global analysis of protein localization in budding yeast","journal":"Nature","year":2003,"url":"https://doi.org/10.1038/nature02026","doi":"10.1038/nature02026","note":"Europe PMC author record matched by affiliation"},{"title":"Global analysis of protein expression in yeast","journal":"Nature","year":2003,"url":"https://doi.org/10.1038/nature02046","doi":"10.1038/nature02046","note":"Europe PMC author record matched by affiliation"},{"title":"Noise in gene expression: origins, consequences, and control","journal":"Science","year":2005,"url":"https://doi.org/10.1126/science.1105891","doi":"10.1126/science.1105891","note":"Europe PMC author record matched by affiliation"}],"orcid":"0000-0002-2649-1018"},"route":"/people/erin-oshea/","neighbours":{"institution":[{"id":"hhmi","kind":"institution","name":"Howard Hughes Medical Institute","route":"/institutions/hhmi/"}],"journal":[{"id":"nature","kind":"journal","name":"Nature","route":"/journals/nature/"},{"id":"science","kind":"journal","name":"Science","route":"/journals/science/"}]}}