{"entity":{"id":"eliezer-van-allen","kind":"person","name":"Eliezer M. Van Allen","aka":[],"tldr":"Computational oncologist who built open tools for interpreting tumour genomes and predicting response.","summary":"Eliezer M. Van Allen is Chief of the Division of Population Sciences at Dana-Farber Brigham Cancer Center and an Associate Member of the Broad Institute. He is a computational oncologist known for building open tools that interpret tumour genomes and predict response to treatment. His selected paper reports the genomic correlates of response to CTLA-4 blockade in metastatic melanoma. His laboratory, spanning Dana-Farber and the Broad, now studies genomic determinants of therapeutic response and resistance in melanoma and prostate cancer, and builds open clinical interpretation and decision-support tools.","asOf":"2026-09-08","links":[{"label":"Van Allen lab","url":"https://vanallenlab.dana-farber.org"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Van%20Allen%20EM%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["melanoma","prostate"],"sections":[],"technologies":["cgp","ai-trial-matching"],"targets":[],"drugs":[],"companies":[],"institutions":["dana-farber"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Chief, Division of Population Sciences; Associate Member, Broad Institute","institutionId":"dana-farber","specialisms":["Computational oncology","Cancer genomics","Precision medicine","AI in oncology"],"profiles":[{"label":"Van Allen lab","url":"https://vanallenlab.dana-farber.org"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Van%20Allen%20EM%5BAuthor%5D"}],"papers":[{"title":"Genomic correlates of response to CTLA-4 blockade in metastatic melanoma","journal":"Science","year":2015,"url":"https://doi.org/10.1126/science.aad0095","doi":"10.1126/science.aad0095"}],"orcid":"0000-0002-0201-4444"},"route":"/people/eliezer-van-allen/","neighbours":{"cancer":[{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"technology":[{"id":"ai-trial-matching","kind":"technology","name":"AI trial matching & clinical decision support","route":"/technologies/ai-trial-matching/"},{"id":"cgp","kind":"technology","name":"Comprehensive genomic profiling","route":"/technologies/cgp/"}],"institution":[{"id":"dana-farber","kind":"institution","name":"Dana-Farber Brigham Cancer Center","route":"/institutions/dana-farber/"}]}}