{"entity":{"id":"eikon-therapeutics","kind":"company","name":"Eikon Therapeutics","aka":[],"tldr":"Eikon Therapeutics is a United States-based biotechnology company running 6 late-stage cancer trials of EIK1001, EIK1004-001 (IMP1707-001) and IMP1734 in melanoma, non-small-cell lung cancer and gastric & gastro-oesophageal junction cancer.","summary":"Eikon Therapeutics, based in Millbrae, California, the United States, is a biotechnology company. A drug discovery company that also has offices in New York and Jersey City and lists clinical-stage oncology, immunology and neuroscience programmes on its pipeline page, including TLR7/8, PARP1, PARP1-CNS penetrant, AR, VCP and AR-v7 targeted programmes. On ClinicalTrials.gov it is the lead sponsor of 6 recruiting or active phase 2 and phase 3 interventional cancer trials (2 in phase 3), testing EIK1001, EIK1004-001 (IMP1707-001), IMP1734 and EIK1005 in melanoma, non-small-cell lung cancer, gastric & gastro-oesophageal junction cancer, colorectal cancer and endometrial cancer. The largest, NCT07365319 (A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer), plans to enrol 750 participants. Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.","asOf":"2026-09-11","links":[{"label":"Official website","url":"https://www.eikontx.com"},{"label":"ClinicalTrials.gov: trials led by Eikon Therapeutics","url":"https://clinicaltrials.gov/search?lead=Eikon%20Therapeutics"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["melanoma","nsclc","gastric","colorectal","endometrial"],"sections":[],"technologies":[],"targets":[],"drugs":["eik1001","eik1005","imp1734"],"companies":["lux-capital"],"institutions":[],"pathways":[],"terms":[],"trials":["nct06246110","nct06907043"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Millbrae, California","country":"US","companyType":"biotech","website":"https://www.eikontx.com","investors":[],"funding":[]},"route":"/companies/eikon-therapeutics/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"eik1001","kind":"drug","name":"EIK1001","route":"/drugs/eik1001/"},{"id":"eik1005","kind":"drug","name":"EIK1005","route":"/drugs/eik1005/"},{"id":"imp1734","kind":"drug","name":"IMP1734","route":"/drugs/imp1734/"}],"company":[{"id":"lux-capital","kind":"company","name":"Lux Capital","route":"/companies/lux-capital/"}],"trial":[{"id":"nct06253130","kind":"trial","name":"A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors","route":"/trials/nct06253130/"},{"id":"nct06246110","kind":"trial","name":"A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC","route":"/trials/nct06246110/"},{"id":"nct07365319","kind":"trial","name":"A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer","route":"/trials/nct07365319/"},{"id":"nct06907043","kind":"trial","name":"A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors.","route":"/trials/nct06907043/"},{"id":"nct07262619","kind":"trial","name":"EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Partic","route":"/trials/nct07262619/"},{"id":"nct06697301","kind":"trial","name":"Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma","route":"/trials/nct06697301/"}]}}