{"entity":{"id":"daiichi-sankyo","kind":"company","name":"Daiichi Sankyo","aka":[],"tldr":"Daiichi Sankyo is the Japanese company whose DXd payload technology created the best ADC platform in the industry.","summary":"Daiichi Sankyo, based in Tokyo and listed as 4568.T, is the Japanese company whose DXd payload technology created the leading antibody-drug conjugate platform in the industry. Five DXd ADCs are in late development: trastuzumab deruxtecan and datopotamab deruxtecan with AstraZeneca, and patritumab deruxtecan against HER3, ifinatamab deruxtecan against B7-H3 and raludotatug deruxtecan against CDH6 with Merck, and Enhertu alone sells more than four billion dollars a year. OnCo links it to the DESTINY-Breast03, 04 and 06 papers that moved T-DXd into HER2-low and ultralow breast cancer, to TROPION-Breast01, to quizartinib and QuANTUM-First in FLT3-ITD leukaemia, and to the National Cancer Center Hospital investigators who ran its early trials. Whether the platform can keep winning as rival topoisomerase payloads arrive is the open question. Each ADC has its own page.","asOf":"2026-09-04","wikipedia":"https://en.wikipedia.org/wiki/Daiichi_Sankyo","links":[{"label":"Official website","url":"https://www.daiichisankyo.com"}],"tags":[],"related":[],"cancers":[],"sections":["adcs"],"technologies":[],"targets":[],"drugs":["trastuzumab-deruxtecan","datopotamab-deruxtecan","patritumab-deruxtecan","ifinatamab-deruxtecan","raludotatug-deruxtecan"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct06899126","nct05215340","nct05555732","nct06819007","nct06174987","nct07022483","nct04619004","nct06172478","nct06644768","nct05280470","nct06362252","nct04145622","nct06864169","nct06731478","nct05875168","nct07720284","nct06330064","nct07405151","nct07630974","nct04488822","nct07129993","nct07286149","nct07060807","nct04538742","nct06797635","nct06863272","nct06596694","nct06686394","nct04938817","nct06941272","nct04703192","nct06112379","nct04379596","nct06780098","nct06644781","nct06780111","nct05950945","nct06271837","nct06445972","nct04458272","nct06824168","nct05460273","nct07220616","nct06780085","nct06660654","nct03793478","nct07205822"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Tokyo","country":"JP","companyType":"pharma","website":"https://www.daiichisankyo.com","ticker":"4568.T","investors":[],"funding":[]},"route":"/companies/daiichi-sankyo/","neighbours":{"section":[{"id":"adcs","kind":"section","name":"Antibody-Drug 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