{"entity":{"id":"clear-gene","kind":"company","name":"Clear Gene","aka":[],"tldr":"Clear Gene is developing tests that tell a surgeon, quickly, whether all of the cancer was removed during an operation.","summary":"Clear Gene develops molecular assays for surgical margin assessment, intended to show whether tumour tissue remains at the edge of a resection so that re-operation rates can fall, with breast surgery as the first application. The tests use epigenetic and genomic markers rather than conventional histology. The company remains active in the YC directory; it has not announced a marketed product or pivotal validation in a primary source found at the time of checking.","asOf":"2026-09-10","links":[{"label":"Y Combinator profile","url":"https://www.ycombinator.com/companies/clear-gene"},{"label":"Official website","url":"https://cleargene.com"}],"tags":["yc"],"related":[],"cancers":["tnbc","breast-hr-positive","breast-her2-positive"],"sections":["diagnostics","surgery"],"technologies":["methylation-profiling"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"San Carlos, CA","country":"US","companyType":"diagnostics","website":"https://cleargene.com","stage":"startup","ycBatch":"S18","investors":["y-combinator"],"funding":[]},"route":"/companies/clear-gene/","neighbours":{"cancer":[{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"section":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"methylation-profiling","kind":"technology","name":"DNA methylation profiling","route":"/technologies/methylation-profiling/"}],"company":[{"id":"y-combinator","kind":"company","name":"Y Combinator","route":"/companies/y-combinator/"}]}}