{"entity":{"id":"chemotherapy","kind":"section","name":"Chemotherapy","aka":[],"tldr":"Drugs that kill fast-dividing cells. Still the backbone of many cures, and now the warhead inside smarter drugs.","summary":"Chemotherapy collects the cytotoxic drugs that kill fast-dividing cells: platinums, taxanes, anthracyclines, antimetabolites and topoisomerase inhibitors. These agents remain curative in several cancers and now serve as the payloads inside antibody-drug conjugates, so progress lies in dosing, sequencing, biomarker-guided de-escalation and toxicity mitigation rather than in new cytotoxics alone. Technologies that point here include cytotoxic chemotherapy, platinum agents, topoisomerase-I inhibitors, autologous and tandem stem cell transplant, PET-adapted therapy, HIPEC and PIPAC, TACE, chronotherapy and metabolic therapy. Scalp cooling and the company PharmaMar also link to this section.","asOf":"2026-09-04","links":[{"label":"NCI: Chemotherapy to treat cancer","url":"https://www.cancer.gov/about-cancer/treatment/types/chemotherapy"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["cancer-chemotherapy-and-pharmacology","gan-to-kagaku-ryoho","journal-of-oncology-pharmacy-practice"],"dependsOn":[],"notes":[],"order":6,"icon":"flask"},"route":"/fronts/chemotherapy/","neighbours":{"journal":[{"id":"cancer-chemotherapy-and-pharmacology","kind":"journal","name":"Cancer chemotherapy and pharmacology","route":"/journals/cancer-chemotherapy-and-pharmacology/"},{"id":"gan-to-kagaku-ryoho","kind":"journal","name":"Gan to kagaku ryoho. 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