{"entity":{"id":"charu-aggarwal","kind":"person","name":"Charu Aggarwal","aka":[],"tldr":"Showed that adding blood-based sequencing to tissue testing finds more targetable lung cancer mutations.","summary":"Charu Aggarwal is the Leslye M. Heisler Professor for Lung Cancer Excellence and Section Chief of Thoracic and Head & Neck Medical Oncology at the Abramson Cancer Center, University of Pennsylvania. She is a thoracic oncologist known for plasma next-generation sequencing studies showing that adding blood-based testing to tissue testing finds more targetable lung cancer mutations, work that changed how metastatic lung cancer is genotyped. Her selected paper reports the clinical implications of plasma-based genotyping for delivering personalised therapy in metastatic non-small-cell lung cancer. She now leads immunotherapy and head and neck cancer trials at Penn.","asOf":"2026-09-08","links":[{"label":"Penn profile","url":"https://www.pennmedicine.org/providers/profile/charu-aggarwal"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Aggarwal%20C%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["nsclc","head-and-neck"],"sections":[],"technologies":["liquid-biopsy","cgp"],"targets":[],"drugs":[],"companies":[],"institutions":["penn-abramson"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["jama-oncology"],"dependsOn":[],"notes":[],"role":"Leslye M. Heisler Professor for Lung Cancer Excellence; Section Chief, Thoracic and Head & Neck Medical Oncology","institutionId":"penn-abramson","specialisms":["Lung cancer","Liquid biopsy","Immunotherapy"],"profiles":[{"label":"Penn profile","url":"https://www.pennmedicine.org/providers/profile/charu-aggarwal"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Aggarwal%20C%5BAuthor%5D"}],"papers":[{"title":"Clinical implications of plasma-based genotyping with the delivery of personalized therapy in metastatic non-small cell lung cancer","journal":"JAMA Oncology","year":2019,"url":"https://doi.org/10.1001/jamaoncol.2018.4305","doi":"10.1001/jamaoncol.2018.4305"}]},"route":"/people/charu-aggarwal/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"technology":[{"id":"cgp","kind":"technology","name":"Comprehensive genomic profiling","route":"/technologies/cgp/"},{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"}],"institution":[{"id":"penn-abramson","kind":"institution","name":"Abramson Cancer Center, University of Pennsylvania","route":"/institutions/penn-abramson/"}],"journal":[{"id":"jama-oncology","kind":"journal","name":"JAMA Oncology","route":"/journals/jama-oncology/"}]}}