{"entity":{"id":"champalimaud","kind":"institution","name":"Champalimaud Foundation, Champalimaud Clinical Centre","aka":["Fundação Champalimaud","Champalimaud Centre for the Unknown"],"tldr":"Lisbon's private research foundation and clinic, known for advanced breast cancer guidelines, digestive cancer surgery and cancer-neuroscience research.","summary":"The Champalimaud Centre for the Unknown opened in 2010 on the Lisbon waterfront as a neuroscience and cancer research institute with an attached clinical centre. Fátima Cardoso directs its breast unit and chairs the international ESO-ESMO Advanced Breast Cancer (ABC) consensus guidelines, the digestive unit is a reference for rectal cancer organ preservation and pancreatic surgery, and the radiation oncology department was among the first in Europe to install new-generation stereotactic and MR-guided systems. Research groups study cancer-nervous system interactions, exosome-mediated metastasis (Bruno Costa-Silva), tumour immunology and computational oncology. The foundation also runs the Champalimaud Vision Award and public engagement programmes.","asOf":"2026-09-09","links":[{"label":"Homepage (archived copy)","url":"https://web.archive.org/web/20200904070334/https://fchampalimaud.org/en/"}],"tags":[],"related":[],"cancers":["breast-hr-positive","breast-her2-positive","colorectal","pancreatic"],"sections":["radiation","surgery"],"technologies":["sbrt","mr-linac","robotic-surgery","liquid-biopsy"],"targets":[],"drugs":[],"companies":[],"institutions":["esmo","ipo-lisboa"],"pathways":[],"terms":[],"trials":[],"people":["leonor-beleza","teresa-cotta-dias"],"bottlenecks":["b-metastasis-biology"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Lisbon","country":"PT","lat":38.693,"lng":-9.221,"institutionType":"research-institute","website":"https://web.archive.org/web/20200904070334/https://fchampalimaud.org/en/","programs":["Advanced Breast Cancer (ABC) guidelines","Digestive oncology and rectal organ preservation","Precision radiotherapy","Cancer and neuroscience research"]},"route":"/institutions/champalimaud/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"section":[{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"},{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mr-linac","kind":"technology","name":"MR-guided adaptive radiotherapy","route":"/technologies/mr-linac/"},{"id":"robotic-surgery","kind":"technology","name":"Robotic & minimally invasive surgery","route":"/technologies/robotic-surgery/"},{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"institution":[{"id":"esmo","kind":"institution","name":"European Society for Medical Oncology (ESMO)","route":"/institutions/esmo/"},{"id":"ipo-lisboa","kind":"institution","name":"Instituto Português de Oncologia de Lisboa Francisco Gentil","route":"/institutions/ipo-lisboa/"}],"person":[{"id":"leonor-beleza","kind":"person","name":"Leonor Beleza","route":"/people/leonor-beleza/"},{"id":"teresa-cotta-dias","kind":"person","name":"Teresa Cotta-Dias","route":"/people/teresa-cotta-dias/"}],"bottleneck":[{"id":"b-metastasis-biology","kind":"bottleneck","name":"Metastasis is understood least and studied last","route":"/bottlenecks/b-metastasis-biology/"}]}}