{"entity":{"id":"boris-pasche","kind":"person","name":"Boris C. Pasche","aka":[],"tldr":"Oncologist who leads the Barbara Ann Karmanos Cancer Institute in Detroit as President and CEO and chairs the Department of Oncology at Wayne State University.","summary":"Boris C. Pasche (MD, PhD, FACP) leads the Barbara Ann Karmanos Cancer Institute in Detroit as President and Chief Executive Officer, according to the institute's English Wikipedia article, which describes the institute as being 'under the direction of President and CEO Boris C. Pasche'. Karmanos is a National Cancer Institute designated comprehensive cancer centre, and its academic partner is Wayne State University School of Medicine, whose Department of Oncology page lists him as Chair. The Karmanos website itself could not be fetched when checked.","asOf":"2026-09-10","links":[{"label":"Source: Wikipedia article on the institute (names President and CEO)","url":"https://en.wikipedia.org/wiki/Barbara_Ann_Karmanos_Cancer_Institute"},{"label":"Source: Wayne State Department of Oncology page (Chair)","url":"https://oncology.med.wayne.edu/"}],"tags":["leadership","clinician-scientist","comprehensive-cancer-centre"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["karmanos"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["clinical-cancer-research","jama"],"dependsOn":[],"notes":[],"role":"President and Chief Executive Officer, Barbara Ann Karmanos Cancer Institute","institutionId":"karmanos","specialisms":["Medical oncology","Cancer genetics","Cancer centre leadership"],"profiles":[{"label":"Wayne State University Department of Oncology","url":"https://oncology.med.wayne.edu/"},{"label":"Wikipedia: Barbara Ann Karmanos Cancer Institute","url":"https://en.wikipedia.org/wiki/Barbara_Ann_Karmanos_Cancer_Institute"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Pasche+B%5BAuthor%5D"}],"papers":[{"title":"TGFβ in Pancreas and Colorectal Cancer: Opportunities to Overcome Therapeutic Resistance","journal":"Clinical Cancer Research","year":2024,"doi":"10.1158/1078-0432.ccr-24-0468"},{"title":"TGF-β signaling alterations and susceptibility to colorectal cancer","journal":"Human Molecular Genetics","year":2007,"doi":"10.1093/hmg/ddl486"},{"title":"One Step Forward Toward Identification of the Genetic Signature of Glioblastomas","journal":"JAMA","year":2009,"doi":"10.1001/jama.2009.1023"}]},"route":"/people/boris-pasche/","neighbours":{"institution":[{"id":"karmanos","kind":"institution","name":"Barbara Ann Karmanos Cancer Institute","route":"/institutions/karmanos/"}],"journal":[{"id":"clinical-cancer-research","kind":"journal","name":"Clinical Cancer Research","route":"/journals/clinical-cancer-research/"},{"id":"jama","kind":"journal","name":"JAMA","route":"/journals/jama/"}]}}