{"entity":{"id":"birmingham-cancer-centre","kind":"institution","name":"University Hospitals Birmingham / University of Birmingham Cancer Research Centre","aka":["Queen Elizabeth Hospital Birmingham","CRUK Clinical Trials Unit Birmingham","Institute of Cancer and Genomic Sciences"],"tldr":"Birmingham's Queen Elizabeth Hospital is the West Midlands' cancer centre, with one of the UK's largest stem cell transplant programmes; the university's Cancer Research UK Clinical Trials Unit ran POUT in upper-tract urothelial cancer and FOxTROT in colon cancer, plus paediatric leukaemia trials.","summary":"The Queen Elizabeth Hospital Birmingham is the tertiary cancer centre for the West Midlands, with one of the largest stem cell transplant programmes in the UK and a regional CAR-T service. The University of Birmingham's Cancer Research UK Clinical Trials Unit has run practice-defining trials such as POUT (adjuvant chemotherapy in upper-tract urothelial cancer), FOxTROT with Leeds, and numerous paediatric and leukaemia trials for the UK's children's cancer groups. The Institute of Cancer and Genomic Sciences studies Epstein-Barr virus-driven cancers, lymphoma biology and cancer inflammation, and Birmingham Children's Hospital is a principal treatment centre. The city hosts a CRUK Centre and the Birmingham Health Partners academic health science system.","asOf":"2026-09-09","links":[{"label":"UHB cancer services","url":"https://www.uhb.nhs.uk/services/cancer"},{"label":"CRUK Clinical Trials Unit","url":"https://www.birmingham.ac.uk/research/crctu"}],"tags":[],"related":[],"cancers":["urothelial","colorectal","all-leukemia","hodgkin-lymphoma","pancreatic","rectal-cancer","nsclc","lung-cancer","skin-cancer","merkel-cell-carcinoma"],"sections":["chemotherapy","cell-therapy"],"technologies":["car-t","cytotoxic-chemotherapy","allogeneic-cell-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":["cruk","leeds-cancer-centre"],"pathways":[],"terms":["neoadjuvant-adjuvant"],"trials":["foxtrot","star-trec","national-lung-matrix-trial","violet","mcc-rational-treatment"],"people":["jonathan-brotherton","hisham-mehanna","dion-morton","gary-middleton"],"bottlenecks":["b-trial-design"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Birmingham","country":"GB","lat":52.453,"lng":-1.939,"institutionType":"hospital","website":"https://www.uhb.nhs.uk/services/cancer","university":"University of Birmingham","programs":["CRUK Clinical Trials Unit","Stem cell transplantation and CAR-T","Urothelial and colorectal trials","Paediatric oncology","EBV and lymphoma research"]},"route":"/institutions/birmingham-cancer-centre/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"urothelial","kind":"cancer","name":"Bladder & urothelial cancer","route":"/cancers/urothelial/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"gallbladder","kind":"cancer","name":"Gallbladder cancer","route":"/cancers/gallbladder/"},{"id":"hodgkin-lymphoma","kind":"cancer","name":"Hodgkin lymphoma","route":"/cancers/hodgkin-lymphoma/"},{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"},{"id":"merkel-cell-carcinoma","kind":"cancer","name":"Merkel cell carcinoma","route":"/cancers/merkel-cell-carcinoma/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"},{"id":"skin-cancer","kind":"cancer","name":"Skin cancer (all types)","route":"/cancers/skin-cancer/"}],"section":[{"id":"cell-therapy","kind":"section","name":"Cell Therapy","route":"/fronts/cell-therapy/"},{"id":"chemotherapy","kind":"section","name":"Chemotherapy","route":"/fronts/chemotherapy/"}],"technology":[{"id":"allogeneic-cell-therapy","kind":"technology","name":"Allogeneic (off-the-shelf) cell therapy","route":"/technologies/allogeneic-cell-therapy/"},{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"institution":[{"id":"ammf","kind":"institution","name":"AMMF, the Cholangiocarcinoma Charity","route":"/institutions/ammf/"},{"id":"cruk","kind":"institution","name":"Cancer Research UK","route":"/institutions/cruk/"},{"id":"leeds-cancer-centre","kind":"institution","name":"Leeds Cancer Centre, St James's University Hospital","route":"/institutions/leeds-cancer-centre/"},{"id":"west-midlands-cancer-alliance","kind":"institution","name":"West Midlands Cancer Alliance","route":"/institutions/west-midlands-cancer-alliance/"}],"term":[{"id":"neoadjuvant-adjuvant","kind":"term","name":"Neoadjuvant / adjuvant / perioperative","route":"/terms/neoadjuvant-adjuvant/"}],"trial":[{"id":"foxtrot","kind":"trial","name":"FOxTROT","route":"/trials/foxtrot/"},{"id":"national-lung-matrix-trial","kind":"trial","name":"National Lung Matrix Trial","route":"/trials/national-lung-matrix-trial/"},{"id":"new-epoc","kind":"trial","name":"New EPOC","route":"/trials/new-epoc/"},{"id":"precision-panc","kind":"trial","name":"Precision-Panc","route":"/trials/precision-panc/"},{"id":"mcc-rational-treatment","kind":"trial","name":"Rational treatment selection for Merkel cell carcinoma","route":"/trials/mcc-rational-treatment/"},{"id":"star-trec","kind":"trial","name":"STAR-TREC","route":"/trials/star-trec/"},{"id":"violet","kind":"trial","name":"VIOLET","route":"/trials/violet/"}],"person":[{"id":"dion-morton","kind":"person","name":"Dion Morton","route":"/people/dion-morton/"},{"id":"gary-middleton","kind":"person","name":"Gary Middleton","route":"/people/gary-middleton/"},{"id":"hisham-mehanna","kind":"person","name":"Hisham Mehanna","route":"/people/hisham-mehanna/"},{"id":"jonathan-brotherton","kind":"person","name":"Jonathan Brotherton","route":"/people/jonathan-brotherton/"}],"bottleneck":[{"id":"b-trial-design","kind":"bottleneck","name":"Trial design, endpoints and cost","route":"/bottlenecks/b-trial-design/"}],"collection":[{"id":"uk-hpb-specialist-centres","kind":"collection","name":"UK specialist HPB cancer centres","route":"/collections/uk-hpb-specialist-centres/"}]}}