{"entity":{"id":"biobanking","kind":"technology","name":"Biobanking and tissue procurement","aka":[],"tldr":"Freezers full of consented tumour samples with matched clinical data, which every biomarker and drug programme depends on.","summary":"Academic biobanks (MD Anderson, Mayo, UK Biobank for germline, Karolinska, Hartwig for WGS), commercial procurement (Discovery Life Sciences, Indivumed, BioIVT, Precision for Medicine, iSpecimen marketplace), and living biobanks of organoids and PDX (Hubrecht Organoid Technology, Champions Oncology, HCMI) supply tissue, blood, and models for target validation and diagnostic development. Consent breadth, annotation depth, and pre-analytic standardisation determine value.","status":"established","asOf":"2026-09-08","links":[{"label":"NCI Best Practices for Biospecimen Resources","url":"https://biospecimens.cancer.gov/bestpractices/"}],"tags":["supporting"],"related":["uk-biobank"],"cancers":[],"sections":["drug-discovery","diagnostics"],"technologies":["organoids","pdx-models","functional-drug-testing"],"targets":[],"drugs":[],"companies":["discovery-life-sciences","indivumed","hub-organoids"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"principle":"Consented collection at surgery or biopsy, controlled fixation or snap-freezing, LIMS tracking, and linked de-identified clinical follow-up.","strengths":["Enables retrospective biomarker validation","Living biobanks allow functional testing"],"limitations":["Consent and governance","Pre-analytic variability","Under-representation of many populations"]},"route":"/technologies/biobanking/","neighbours":{"collection":[{"id":"uk-biobank","kind":"collection","name":"UK Biobank","route":"/collections/uk-biobank/"}],"section":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"drug-discovery","kind":"section","name":"Drug Discovery Platforms","route":"/fronts/drug-discovery/"}],"technology":[{"id":"functional-drug-testing","kind":"technology","name":"Functional (ex vivo) drug testing","route":"/technologies/functional-drug-testing/"},{"id":"organoids","kind":"technology","name":"Patient-derived organoids","route":"/technologies/organoids/"},{"id":"pdx-models","kind":"technology","name":"Patient-derived xenografts","route":"/technologies/pdx-models/"},{"id":"preanalytics-sample-stabilisation","kind":"technology","name":"Pre-analytics: blood-collection tubes and tissue fixation","route":"/technologies/preanalytics-sample-stabilisation/"}],"company":[{"id":"discovery-life-sciences","kind":"company","name":"Discovery Life Sciences","route":"/companies/discovery-life-sciences/"},{"id":"hub-organoids","kind":"company","name":"HUB Organoids","route":"/companies/hub-organoids/"},{"id":"indivumed","kind":"company","name":"Indivumed","route":"/companies/indivumed/"}],"person":[{"id":"henrietta-lacks","kind":"person","name":"Henrietta Lacks","route":"/people/henrietta-lacks/"}]}}