{"entity":{"id":"bclc-staging","kind":"term","name":"BCLC staging","aka":[],"tldr":"The liver-cancer staging system that combines tumour size, liver function and fitness to recommend treatment: ablation or surgery, transplant, TACE, or drugs.","summary":"Barcelona Clinic Liver Cancer stages 0/A (very early/early: ablation, resection, transplant), B (intermediate: TACE, or systemic therapy for high burden), C (advanced: systemic therapy) and D (terminal). The 2022 update introduced treatment-stage migration and systemic therapy for some BCLC-B patients. Used in guidelines worldwide and as a trial-eligibility framework.","asOf":"2026-09-07","wikipedia":"https://en.wikipedia.org/wiki/Hepatocellular_carcinoma","links":[{"label":"Reig et al., BCLC strategy for prognosis prediction and treatment recommendation: the 2022 update (Journal of Hepatology 2022)","url":"https://doi.org/10.1016/j.jhep.2021.11.018"}],"tags":[],"related":[],"cancers":["hcc"],"sections":[],"technologies":["tace","thermal-ablation","liver-transplant-oncology"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"category":"Clinical"},"route":"/terms/bclc-staging/","neighbours":{"cancer":[{"id":"hcc-early","kind":"cancer","name":"Early hepatocellular carcinoma (BCLC 0 and A)","route":"/cancers/hcc-early/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"hcc-intermediate","kind":"cancer","name":"Intermediate hepatocellular carcinoma (BCLC B)","route":"/cancers/hcc-intermediate/"}],"technology":[{"id":"liver-transplant-oncology","kind":"technology","name":"Liver transplantation for cancer (Milan criteria and beyond)","route":"/technologies/liver-transplant-oncology/"},{"id":"thermal-ablation","kind":"technology","name":"Thermal ablation (RFA, microwave, cryo)","route":"/technologies/thermal-ablation/"},{"id":"tace","kind":"technology","name":"Transarterial chemoembolisation (TACE)","route":"/technologies/tace/"}],"term":[{"id":"child-pugh-albi","kind":"term","name":"Child-Pugh and ALBI liver-function scores","route":"/terms/child-pugh-albi/"},{"id":"child-pugh","kind":"term","name":"Child-Pugh score","route":"/terms/child-pugh/"},{"id":"cirrhosis","kind":"term","name":"Cirrhosis","route":"/terms/cirrhosis/"},{"id":"staging-systems","kind":"term","name":"Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC)","route":"/terms/staging-systems/"},{"id":"downstaging","kind":"term","name":"Downstaging and conversion therapy","route":"/terms/downstaging/"},{"id":"li-rads","kind":"term","name":"LI-RADS (Liver Imaging Reporting and Data System)","route":"/terms/li-rads/"},{"id":"portal-vein-tumour-thrombus","kind":"term","name":"Portal vein tumour thrombus (macrovascular invasion)","route":"/terms/portal-vein-tumour-thrombus/"},{"id":"tace-term","kind":"term","name":"TACE (transarterial chemoembolisation)","route":"/terms/tace-term/"}]}}