{"entity":{"id":"ascentawits-pharmaceuticals","kind":"company","name":"Ascentawits Pharmaceuticals","aka":["Ascentawits Pharmaceuticals, Ltd"],"tldr":"Ascentawits Pharmaceuticals is a China-based biotechnology company running 2 late-stage cancer trials of AST-3424 and AST-001 in hepatocellular carcinoma and pancreatic ductal adenocarcinoma.","summary":"Ascentawits Pharmaceuticals, based in Shenzhen, China, is a biotechnology company. Ascentawits Pharmaceuticals (Shenzhen Ascenta Wits Pharmaceutical Technology Co., Ltd.) develops small molecule-drug conjugates as targeted cancer therapeutics. On ClinicalTrials.gov it is the lead sponsor of 2 recruiting or active phase 2 and phase 3 interventional cancer trials, testing AST-3424 and AST-001 in hepatocellular carcinoma and pancreatic ductal adenocarcinoma. The largest, NCT06245330 (A Phase I/II Study of AST-001 in Subjects With Advanced Solid Tumours), plans to enrol 180 participants. Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.","asOf":"2026-09-11","links":[{"label":"Official website","url":"https://www.ascentawits.com"},{"label":"ClinicalTrials.gov: trials led by Ascentawits Pharmaceuticals","url":"https://clinicaltrials.gov/search?lead=Ascentawits%20Pharmaceuticals%2C%20Ltd"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["hcc","pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct06245330","nct06239155"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Shenzhen","country":"CN","companyType":"biotech","website":"https://www.ascentawits.com","investors":[],"funding":[]},"route":"/companies/ascentawits-pharmaceuticals/","neighbours":{"cancer":[{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"trial":[{"id":"nct06245330","kind":"trial","name":"A Phase I/II Study of AST-001 in Subjects With Advanced Solid Tumors","route":"/trials/nct06245330/"},{"id":"nct06239155","kind":"trial","name":"A Phase I/II Study of AST-3424 in Subjects With Advanced Solid Tumors","route":"/trials/nct06239155/"}]}}