{"entity":{"id":"armando-giuliano","kind":"person","name":"Armando E. Giuliano","aka":[],"tldr":"Brought sentinel node biopsy to breast cancer and led ACOSOG Z0011, which ended routine axillary dissection for many women.","summary":"Armando Giuliano performed the first sentinel lymph node biopsies for breast cancer in the early 1990s and then led ACOSOG Z0011, the trial showing women with one or two positive sentinel nodes treated with breast conservation and radiotherapy do not need completion axillary dissection. The ten-year results changed practice worldwide and spared hundreds of thousands of women lymphoedema. He continues to lead surgical trials at Cedars-Sinai.","asOf":"2026-09-10","wikipedia":"https://en.wikipedia.org/wiki/Armando_E._Giuliano","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Giuliano%20AE%5BAuthor%5D%20sentinel%20Z0011"}],"tags":["breast","surgery","de-escalation"],"related":[],"cancers":["breast-hr-positive"],"sections":[],"technologies":["sentinel-node"],"targets":[],"drugs":[],"companies":[],"institutions":["cedars-sinai-cancer"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Executive Vice Chair of Surgery, Cedars-Sinai Medical Center","institutionId":"cedars-sinai-cancer","specialisms":["Breast surgical oncology","Sentinel lymph node biopsy","Axillary de-escalation"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Giuliano%20AE%5BAuthor%5D%20sentinel%20Z0011"}],"papers":[{"title":"Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis (ACOSOG Z0011)","journal":"JAMA","year":2017,"doi":"10.1001/jama.2017.11470"},{"title":"Lymphatic mapping and sentinel lymphadenectomy for breast cancer","journal":"Annals of Surgery","year":1994,"doi":"10.1097/00000658-199409000-00015"}],"orcid":"0000-0002-5421-945X"},"route":"/people/armando-giuliano/","neighbours":{"cancer":[{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"}],"technology":[{"id":"sentinel-node","kind":"technology","name":"Sentinel lymph node biopsy","route":"/technologies/sentinel-node/"}],"institution":[{"id":"cedars-sinai-cancer","kind":"institution","name":"Cedars-Sinai Cancer","route":"/institutions/cedars-sinai-cancer/"}]}}