{"entity":{"id":"ann-partridge","kind":"person","name":"Ann H. Partridge","aka":[],"tldr":"Ann Partridge led the POSITIVE trial showing women can safely pause hormone therapy to have a baby.","summary":"Ann H. Partridge is Vice Chair of Medical Oncology and Director of the Program for Young Adults with Breast Cancer at Dana-Farber Brigham Cancer Center. She is known for leading the POSITIVE trial, which showed that women can safely pause endocrine therapy to have a baby, and for the Young Women's Breast Cancer Study. Her selected paper reports interrupting endocrine therapy to attempt pregnancy after breast cancer. She now directs Dana-Farber's adult survivorship and young women's breast cancer programmes, with a focus on fertility and life after cancer.","asOf":"2026-09-08","wikipedia":"https://en.wikipedia.org/wiki/Ann_Partridge","links":[{"label":"Dana-Farber profile","url":"https://www.dana-farber.org/find-a-doctor/ann-h-partridge"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Partridge%20AH%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["breast-hr-positive"],"sections":[],"technologies":["endocrine-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":["dana-farber"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Vice Chair of Medical Oncology; Director, Program for Young Adults with Breast Cancer","institutionId":"dana-farber","specialisms":["Young women's breast cancer","Survivorship","Fertility after cancer"],"profiles":[{"label":"Dana-Farber profile","url":"https://www.dana-farber.org/find-a-doctor/ann-h-partridge"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Partridge%20AH%5BAuthor%5D"}],"papers":[{"title":"Interrupting endocrine therapy to attempt pregnancy after breast cancer","journal":"New England Journal of Medicine","year":2023,"url":"https://doi.org/10.1056/NEJMoa2212856","doi":"10.1056/NEJMoa2212856"}],"orcid":"0000-0002-4722-4824"},"route":"/people/ann-partridge/","neighbours":{"cancer":[{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"}],"technology":[{"id":"endocrine-therapy","kind":"technology","name":"Endocrine therapy (SERMs, AIs, SERDs)","route":"/technologies/endocrine-therapy/"}],"institution":[{"id":"bcrf","kind":"institution","name":"Breast Cancer Research Foundation","route":"/institutions/bcrf/"},{"id":"dana-farber","kind":"institution","name":"Dana-Farber Brigham Cancer Center","route":"/institutions/dana-farber/"}]}}