{"entity":{"id":"andreas-du-bois","kind":"person","name":"Andreas du Bois","aka":[],"tldr":"Surgeon who chairs the German AGO group and led DESKTOP III, proving secondary surgery can extend survival in selected relapsed ovarian cancer.","summary":"Andreas du Bois (Kliniken Essen-Mitte) chairs the AGO ovarian cancer study group, whose trials established carboplatin-paclitaxel as standard and defined the prognostic value of complete cytoreduction. He was principal investigator of DESKTOP III, which showed secondary cytoreductive surgery improves overall survival in AGO-score-positive platinum-sensitive relapse, and of the TRUST trial of primary versus interval surgery.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=du%20Bois%20A%5BAuthor%5D%20ovarian%20DESKTOP"}],"tags":["ovarian","surgery","cooperative-group"],"related":[],"cancers":["ovarian"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["kliniken-essen-mitte"],"pathways":[],"terms":[],"trials":["desktop-iii"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["cancer-wiley"],"dependsOn":[],"notes":[],"role":"Director of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte; Chair, AGO Study Group","institutionId":"kliniken-essen-mitte","specialisms":["Ovarian cancer surgery","Cooperative-group trials","Cytoreductive surgery","Chemotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=du%20Bois%20A%5BAuthor%5D%20ovarian%20DESKTOP"}],"papers":[{"title":"Randomized trial of cytoreductive surgery for relapsed ovarian cancer (DESKTOP III)","journal":"NEJM","year":2021,"doi":"10.1056/NEJMoa2103294"},{"title":"Role of surgical outcome as prognostic factor in advanced epithelial ovarian cancer: a combined exploratory analysis of 3 prospectively randomized phase 3 multicenter trials","journal":"Cancer","year":2009,"doi":"10.1002/cncr.24149"}],"orcid":"0000-0002-8477-506X"},"route":"/people/andreas-du-bois/","neighbours":{"cancer":[{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"}],"institution":[{"id":"kliniken-essen-mitte","kind":"institution","name":"Kliniken Essen-Mitte","route":"/institutions/kliniken-essen-mitte/"}],"trial":[{"id":"desktop-iii","kind":"trial","name":"DESKTOP III / ENGOT-ov20","route":"/trials/desktop-iii/"}],"journal":[{"id":"cancer-wiley","kind":"journal","name":"Cancer","route":"/journals/cancer-wiley/"}]}}