{"entity":{"id":"alex-herrera","kind":"person","name":"Alex F. Herrera","aka":[],"tldr":"Led the SWOG S1826 trial that made nivolumab part of first-line Hodgkin lymphoma treatment.","summary":"Alex Herrera is Chief of the Division of Lymphoma at City of Hope and SWOG Executive Officer for Leukemia, Lymphoma and Myeloma. A haematologist-oncologist specialising in Hodgkin lymphoma and immunotherapy, he was study chair of SWOG S1826, which compared nivolumab-AVD with brentuximab-AVD and led to the 2026 approval of nivolumab in untreated advanced Hodgkin lymphoma. His papers report nivolumab plus AVD in advanced-stage classic Hodgkin lymphoma in the New England Journal of Medicine and interim results of brentuximab vedotin combined with nivolumab in relapsed or refractory Hodgkin lymphoma in Blood. He also works on diffuse large B-cell lymphoma and oversees SWOG's haematologic committees.","asOf":"2026-09-08","links":[{"label":"City of Hope research faculty","url":"https://www.cityofhope.org/research/find-a-researcher"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Herrera%20AF%5BAuthor%5D"},{"label":"Google Scholar","url":"https://scholar.google.com/scholar?q=Alex%20F.%20Herrera"}],"tags":[],"related":[],"cancers":["hodgkin-lymphoma","dlbcl"],"sections":[],"technologies":[],"targets":[],"drugs":["nivolumab","brentuximab-vedotin"],"companies":["swog"],"institutions":["city-of-hope"],"pathways":[],"terms":[],"trials":["swog-s1826"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["blood"],"dependsOn":[],"notes":[],"role":"Chief, Division of Lymphoma, City of Hope; SWOG Executive Officer, Leukemia/Lymphoma/Myeloma","institutionId":"city-of-hope","specialisms":["Hodgkin lymphoma","Immunotherapy","Cooperative group trials"],"profiles":[{"label":"City of Hope research faculty","url":"https://www.cityofhope.org/research/find-a-researcher"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Herrera%20AF%5BAuthor%5D"},{"label":"Google Scholar","url":"https://scholar.google.com/scholar?q=Alex%20F.%20Herrera"}],"papers":[{"title":"Nivolumab+AVD in Advanced-Stage Classic Hodgkin's Lymphoma","journal":"New England Journal of Medicine","year":2024,"url":"https://doi.org/10.1056/NEJMoa2405888","doi":"10.1056/NEJMoa2405888"},{"title":"Interim results of brentuximab vedotin in combination with nivolumab in patients with relapsed or refractory Hodgkin lymphoma","journal":"Blood","year":2018,"url":"https://doi.org/10.1182/blood-2017-10-811224","doi":"10.1182/blood-2017-10-811224"}]},"route":"/people/alex-herrera/","neighbours":{"cancer":[{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"hodgkin-lymphoma","kind":"cancer","name":"Hodgkin lymphoma","route":"/cancers/hodgkin-lymphoma/"}],"drug":[{"id":"brentuximab-vedotin","kind":"drug","name":"Brentuximab vedotin","route":"/drugs/brentuximab-vedotin/"},{"id":"nivolumab","kind":"drug","name":"Nivolumab","route":"/drugs/nivolumab/"}],"company":[{"id":"swog","kind":"company","name":"SWOG Cancer Research Network","route":"/companies/swog/"}],"institution":[{"id":"city-of-hope","kind":"institution","name":"City of Hope","route":"/institutions/city-of-hope/"}],"trial":[{"id":"swog-s1826","kind":"trial","name":"SWOG S1826","route":"/trials/swog-s1826/"}],"journal":[{"id":"blood","kind":"journal","name":"Blood","route":"/journals/blood/"}],"paper":[{"id":"paper-swog-s1826-nivolumab-avd-nejm-2024","kind":"paper","name":"SWOG S1826: nivolumab plus AVD chemotherapy versus brentuximab-AVD for advanced Hodgkin lymphoma in adolescents and adults","route":"/key-papers/paper-swog-s1826-nivolumab-avd-nejm-2024/"}]}}