{"entity":{"id":"alessandro-gronchi","kind":"person","name":"Alessandro Gronchi","aka":[],"tldr":"Sarcoma surgeon who led the ISG-STS 1001 trial of histology-tailored neoadjuvant chemotherapy.","summary":"Alessandro Gronchi is Chair of the Sarcoma Service at the Fondazione IRCCS Istituto Nazionale dei Tumori in Milan, a surgeon whose specialisms are sarcoma surgery, retroperitoneal sarcoma and neoadjuvant chemotherapy. He is known for chairing ISG-STS 1001, the randomised trial that compared histology-tailored neoadjuvant chemotherapy with standard chemotherapy in high-risk soft-tissue sarcoma, and STRASS, which tested preoperative radiotherapy. His Lancet Oncology paper on ISG-STS 1001 set out how tailoring chemotherapy to sarcoma histotype compares with a standard regimen. He continues to lead the sarcoma surgical programme at INT Milan, with his publications listed on PubMed.","asOf":"2026-09-08","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Gronchi%20A%5BAuthor%5D%20sarcoma"}],"tags":[],"related":[],"cancers":["sarcoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["int-milan"],"pathways":[],"terms":[],"trials":["isg-sts-1001"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Chair, Sarcoma Service, Fondazione IRCCS Istituto Nazionale dei Tumori","institutionId":"int-milan","specialisms":["Sarcoma surgery","Retroperitoneal sarcoma","Neoadjuvant chemotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Gronchi%20A%5BAuthor%5D%20sarcoma"}],"papers":[{"title":"Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001)","journal":"Lancet Oncology","year":2017,"doi":"10.1016/S1470-2045(17)30334-0"}],"orcid":"0000-0002-4703-3534"},"route":"/people/alessandro-gronchi/","neighbours":{"cancer":[{"id":"sarcoma","kind":"cancer","name":"Sarcomas (soft tissue, bone, GIST)","route":"/cancers/sarcoma/"}],"institution":[{"id":"esso","kind":"institution","name":"European Society of Surgical Oncology","route":"/institutions/esso/"},{"id":"int-milan","kind":"institution","name":"Fondazione IRCCS Istituto Nazionale dei Tumori","route":"/institutions/int-milan/"}],"trial":[{"id":"isg-sts-1001","kind":"trial","name":"ISG-STS 1001","route":"/trials/isg-sts-1001/"}],"idea":[{"id":"idea-bio2-rare-cancer-telepathology-network","kind":"idea","name":"A same-week expert second opinion for every rare cancer diagnosis","route":"/ideas/idea-bio2-rare-cancer-telepathology-network/"}]}}