{"entity":{"id":"adrian-ochsenbein","kind":"person","name":"Adrian Ochsenbein","aka":[],"tldr":"Bern medical oncology chief whose lab targets leukaemia stem cells and CD70 signalling.","summary":"Adrian Ochsenbein is Chief Physician of Medical Oncology at Inselspital, Bern University Hospital, and a Director of the University Cancer Center Inselspital. His translational research investigates leukaemia stem cells and immune regulation, leading to the clinical development of the anti-CD70 antibody cusatuzumab in acute myeloid leukaemia. He combines a large clinical department with a laboratory programme in tumour immunology.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://www.tumorzentrum.insel.ch/de/ueber-uns/organisation"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ochsenbein+AF%5BAuthor%5D"}],"tags":["leadership","clinician-scientist","leukaemia","immunotherapy"],"related":[],"cancers":["aml","cml"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["inselspital-bern"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Director UCI; Chief Physician, Medical Oncology","institutionId":"inselspital-bern","specialisms":["Medical oncology","Leukaemia stem cells","Tumour immunology"],"profiles":[{"label":"Institution profile","url":"https://www.tumorzentrum.insel.ch/de/ueber-uns/organisation"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ochsenbein+AF%5BAuthor%5D"}],"papers":[{"title":"Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents","journal":"Nature Medicine","year":2020,"url":"https://doi.org/10.1038/s41591-020-0910-8","doi":"10.1038/s41591-020-0910-8"}]},"route":"/people/adrian-ochsenbein/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"cml","kind":"cancer","name":"Chronic myeloid leukaemia (CML)","route":"/cancers/cml/"}],"institution":[{"id":"inselspital-bern","kind":"institution","name":"Inselspital, Bern University Hospital / University Cancer Center Inselspital","route":"/institutions/inselspital-bern/"}]}}