{"entity":{"id":"abdominoperineal-resection","kind":"term","name":"Abdominoperineal resection","aka":["abdominoperineal","abdomino-perineal resection","salvage APR"],"tldr":"Removing the rectum and anus together, leaving a permanent colostomy. Used when a low rectal or anal cancer involves the sphincter.","summary":"The operation through both the abdomen and the perineum removes rectum, anal canal and sphincters, so a permanent end colostomy is unavoidable. For anal squamous cancer it is reserved as salvage after definitive chemoradiation (the Nigro regimen) fails; for low rectal cancers it is being displaced by sphincter-preserving TME, intersphincteric resection and organ-preservation strategies. Perineal wound problems are common and flap reconstruction is often needed.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/Abdominoperineal_resection","links":[{"label":"Wikipedia","url":"https://en.wikipedia.org/wiki/Abdominoperineal_resection"}],"tags":[],"related":["total-mesorectal-excision","stoma","chemoradiation"],"cancers":["colorectal"],"sections":["surgery"],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"category":"Procedures"},"route":"/terms/abdominoperineal-resection/","neighbours":{"term":[{"id":"chemoradiation","kind":"term","name":"Chemoradiation (chemoradiotherapy, CRT)","route":"/terms/chemoradiation/"},{"id":"colectomy","kind":"term","name":"Colectomy","route":"/terms/colectomy/"},{"id":"stoma","kind":"term","name":"Stoma (colostomy, ileostomy, urostomy)","route":"/terms/stoma/"},{"id":"total-mesorectal-excision","kind":"term","name":"Total mesorectal excision (TME)","route":"/terms/total-mesorectal-excision/"}],"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"section":[{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}]}}