{"entity":{"id":"abcsg","kind":"company","name":"Austrian Breast & Colorectal Cancer Study Group","aka":["ABCSG"],"tldr":"Austria's academic breast and colorectal trials group, whose bone-targeted and extended endocrine therapy trials changed breast cancer practice.","summary":"Founded in 1984, ABCSG runs academic trials through Austria's hospitals and partners with the Breast International Group and the US groups on global studies. ABCSG-12 (zoledronic acid with ovarian suppression in premenopausal breast cancer) and ABCSG-18 (adjuvant denosumab) made bone-targeted agents part of adjuvant care, and ABCSG-16 defined how long extended aromatase inhibitor therapy should last. It co-led PALLAS, the adjuvant palbociclib trial, with Alliance Foundation Trials and BIG. Colorectal and pancreatic trials run through the same network.","asOf":"2026-09-09","links":[{"label":"ABCSG","url":"https://www.abcsg.org"},{"label":"Trials","url":"https://www.abcsg.org/studien/"}],"tags":["cooperative-group"],"related":["palbociclib"],"cancers":["breast-hr-positive","breast-her2-positive","colorectal"],"sections":["hormonal","targeted-therapy"],"technologies":["cdk46-inhibitor","endocrine-therapy"],"targets":[],"drugs":[],"companies":["big","alliance-oncology","gbg"],"institutions":[],"pathways":[],"terms":[],"trials":["pallas-penelope-b"],"people":["michael-gnant","christian-singer"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Adjuvant endocrine and bone-targeted therapy (ABCSG-12, -16, -18)","PALLAS (adjuvant palbociclib, with Alliance and BIG)","Colorectal and pancreatic cancer trials"],"provenance":{"editedBy":"OnCo cooperative groups migration (row 251: institution consortium records moved to cooperative-group companies)","editedOn":"2026-09-25"},"hq":"Vienna","country":"AT","companyType":"cooperative-group","website":"https://www.abcsg.org","founded":1984,"investors":[],"funding":[]},"route":"/companies/abcsg/","neighbours":{"drug":[{"id":"palbociclib","kind":"drug","name":"Palbociclib","route":"/drugs/palbociclib/"}],"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"}],"section":[{"id":"hormonal","kind":"section","name":"Hormonal Therapy","route":"/fronts/hormonal/"},{"id":"targeted-therapy","kind":"section","name":"Targeted Therapy","route":"/fronts/targeted-therapy/"}],"technology":[{"id":"cdk46-inhibitor","kind":"technology","name":"CDK4/6 inhibitors","route":"/technologies/cdk46-inhibitor/"},{"id":"endocrine-therapy","kind":"technology","name":"Endocrine therapy (SERMs, AIs, SERDs)","route":"/technologies/endocrine-therapy/"}],"company":[{"id":"alliance-oncology","kind":"company","name":"Alliance for Clinical Trials in Oncology","route":"/companies/alliance-oncology/"},{"id":"big","kind":"company","name":"Breast International Group (BIG)","route":"/companies/big/"},{"id":"gbg","kind":"company","name":"German Breast Group (GBG)","route":"/companies/gbg/"}],"trial":[{"id":"pallas-penelope-b","kind":"trial","name":"PALLAS & PENELOPE-B","route":"/trials/pallas-penelope-b/"}],"person":[{"id":"christian-singer","kind":"person","name":"Christian Singer","route":"/people/christian-singer/"},{"id":"michael-gnant","kind":"person","name":"Michael Gnant","route":"/people/michael-gnant/"}]}}