{"id":"tmprss2","name":"TMPRSS2","symbol":"TMPRSS2","route":"/targets/tmprss2/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11876","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000184012","uniprot":"https://www.uniprot.org/uniprotkb/O15393/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/O15393","open-targets":"https://platform.opentargets.org/target/ENSG00000184012","civic":"https://civicdb.org/genes/7113/summary","oncokb":"https://www.oncokb.org/gene/TMPRSS2","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=TMPRSS2","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=TMPRSS2","depmap":"https://depmap.org/portal/gene/TMPRSS2?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000184012-TMPRSS2","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/7113","omim":"https://www.omim.org/entry/602060"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":["paper-chung-comprehensive-genomic-profiling-prostate-jco-po-2019","paper-ren-chinese-prostate-whole-genome-eur-urol-2018","paper-tcga-molecular-taxonomy-primary-prostate-cell-2015","paper-baca-punctuated-evolution-chromoplexy-cell-2013","paper-grasso-mutational-landscape-lethal-crpc-nature-2012","paper-pettersson-tmprss2-erg-outcome-meta-analysis-cebp-2012","paper-taylor-integrative-genomic-profiling-cancer-cell-2010","paper-tomlins-tmprss2-ets-fusion-science-2005"],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}