{"id":"tgfbr2","name":"TGFBR2","symbol":"TGFBR2","route":"/targets/tgfbr2/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11773","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163513","uniprot":"https://www.uniprot.org/uniprotkb/P37173/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P37173","open-targets":"https://platform.opentargets.org/target/ENSG00000163513","civic":"https://civicdb.org/genes/7048/summary","oncokb":"https://www.oncokb.org/gene/TGFBR2","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=TGFBR2","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=TGFBR2","depmap":"https://depmap.org/portal/gene/TGFBR2?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000163513-TGFBR2","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/7048","omim":"https://www.omim.org/entry/190182"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":["paper-noe-cyst-malignant-progression-genomics-nat-commun-2020","paper-tcga-pancreatic-integrated-characterisation-cancer-cell-2017","paper-calon-stromal-gene-expression-poor-prognosis-colorectal-nat-genet-2015","paper-biankin-pancreatic-exomes-axon-guidance-nature-2012","paper-markowitz-tgfbr2-inactivation-msi-colon-science-1995"],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}