{"id":"steap1","name":"STEAP1","symbol":"STEAP1","route":"/targets/steap1/","asOf":"2026-09-06","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11378","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000164647","uniprot":"https://www.uniprot.org/uniprotkb/Q9UHE8/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q9UHE8","chembl":"https://www.ebi.ac.uk/chembl/explore/target/CHEMBL3712956","open-targets":"https://platform.opentargets.org/target/ENSG00000164647","civic":"https://civicdb.org/genes/26872/summary","oncokb":"https://www.oncokb.org/gene/STEAP1","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=STEAP1","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=STEAP1","depmap":"https://depmap.org/portal/gene/STEAP1?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000164647-STEAP1","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/26872","omim":"https://www.omim.org/entry/604415"}],"products":[{"id":"xaluritamig","name":"Xaluritamig","status":"phase-3","modality":"Bispecific T-cell engager (STEAP1×CD3, XmAb 2+1)","route":"/drugs/xaluritamig/"}],"trials":[{"id":"nct07213674","name":"A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate ","nct":"NCT07213674","phase":"3","status":"recruiting"},{"id":"xalute","name":"XALute","nct":"NCT06691984","phase":"3","status":"active"}],"pathways":[],"companies":["amgen"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}