{"id":"rnf43","name":"RNF43","symbol":"RNF43","route":"/targets/rnf43/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:18505","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000108375","uniprot":"https://www.uniprot.org/uniprotkb/Q68DV7/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q68DV7","open-targets":"https://platform.opentargets.org/target/ENSG00000108375","civic":"https://civicdb.org/genes/54894/summary","oncokb":"https://www.oncokb.org/gene/RNF43","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=RNF43","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=RNF43","depmap":"https://depmap.org/portal/gene/RNF43?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000108375-RNF43","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/54894","omim":"https://www.omim.org/entry/612482"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":["paper-noe-cyst-malignant-progression-genomics-nat-commun-2020","paper-crockett-nagtegaal-serrated-neoplasia-gastroenterology-2019","paper-yaeger-metastatic-colorectal-genomic-landscape-cancer-cell-2018","paper-felsenstein-ipmn-cooccurring-cancer-relatedness-gut-2018","paper-tcga-pancreatic-integrated-characterisation-cancer-cell-2017","paper-bailey-molecular-subtypes-pancreatic-nature-2016","paper-springer-pancreatic-cyst-molecular-classification-gastroenterology-2015","paper-witkiewicz-pancreatic-exomes-utsw-nat-commun-2015","paper-wu-pancreatic-cyst-exomes-rnf43-pnas-2011"],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}