{"id":"notch2","name":"NOTCH2","symbol":"NOTCH2","route":"/targets/notch2/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7882","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000134250","uniprot":"https://www.uniprot.org/uniprotkb/Q04721/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q04721","open-targets":"https://platform.opentargets.org/target/ENSG00000134250","civic":"https://civicdb.org/genes/4853/summary","oncokb":"https://www.oncokb.org/gene/NOTCH2","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=NOTCH2","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=NOTCH2","depmap":"https://depmap.org/portal/gene/NOTCH2?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000134250-NOTCH2","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/4853","omim":"https://www.omim.org/entry/600275"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":["paper-wright-lymphgen-genetic-subtypes-dlbcl-cancer-cell-2020","paper-schmitz-genetics-pathogenesis-dlbcl-nejm-2018","paper-chapuy-molecular-subtypes-dlbcl-nat-med-2018"],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}